Although clinical use of the auditory brainstem response (ABR) to detect retrocochlear
disorders has been largely replaced by imaging in recent years, the discovery of cochlear …

There are multiple etiologies and phenotypes of age-related hearing loss or presbyacusis. In
this review we summarize findings from animal and human studies of presbyacusis …

A common complaint of older adults is difficulty understanding speech, particularly in
challenging listening conditions. Accumulating evidence suggests that these difficulties may …

Aging is associated with auditory nerve (AN) functional deficits and decreased inhibition in
the central auditory system, amplifying central responses in a process referred to here as …

The electrically evoked compound action potential (eCAP) is a direct measure of the
responsiveness of the auditory nerve to electrical stimulation from a cochlear implant (CI) …

Neural coding of the slow amplitude fluctuations of sound (ie, temporal envelope) is thought
to be essential for speech understanding; however, such coding by the human auditory …

Purpose Human auditory nerve (AN) activity estimated from the amplitude of the first
prominent negative peak (N1) of the compound action potential (CAP) is typically quantified …

There are several technical challenges to obtaining high-quality recordings of cochlear
potentials in human electrocochleography (ECochG). These challenges include electrical …

Auditory-nerve fibers are lost steadily with age and as a possible consequence of noise-
induced glutamate excitotoxicity. Auditory-nerve loss in the absence of other cochlear …

Accumulating evidence suggests that cochlear deafferentation may contribute to
suprathreshold deficits observed with or without elevated hearing thresholds, and can lead …