In the past decade, single-cell technologies have proliferated and improved from their
technically challenging beginnings to become common laboratory methods capable of …

Research into aging constitutes a pivotal endeavor aimed at elucidating the underlying
biological mechanisms governing aging and age-associated diseases, as well as promoting …

Chronic allograft dysfunction (CAD), characterized histologically by interstitial fibrosis and
tubular atrophy, is the major cause of kidney allograft loss. Here, using single nuclei RNA …

Pregnant women are often prescribed or abuse opioid drugs. The placenta is likely the key
to understanding how opioids cause adverse pregnancy outcomes. Maternal oxycodone …

Biobanking of tissue from clinically obtained kidney biopsies for later analysis with multiomic
approaches, such as single-cell technologies, proteomics, metabolomics, and the different …

Long-read single-cell transcriptomics (scRNA-Seq) is revolutionizing the way we profile
heterogeneity in disease. Traditional short-read scRNA-Seq methods are limited in their …

Tumor heterogeneity is a significant factor influencing cancer treatment effectiveness and
can arise from genetic, epigenetic, and phenotypic variations among cancer cells …

Single-cell and single-nucleus RNA sequencing have become common laboratory
applications due to the wealth of transcriptomic information that they provide. Single nucleus …

Single cell sequencing technologies have rapidly advanced in the last decade and are
increasingly applied to gain unprecedented insights by deconstructing complex biology to its …

The single cell RNA sequencing technique has been particularly used during the last years,
allowing major discoveries. However, the widespread application of this analysis has …