Mesenchymal stem cell-derived exosomes: applications in regenerative medicine
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …
are then released into the extracellular space through a merging of the multivesicular body …
Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading
J Rädler, D Gupta, A Zickler, SEL Andaloussi - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …
applications in various diseases. These natural nanoparticles benefit from favorable safety …
[HTML][HTML] Exosome-based liquid biopsies in cancer: opportunities and challenges
W Yu, J Hurley, D Roberts, SK Chakrabortty… - Annals of …, 2021 - Elsevier
Liquid biopsy in cancer has gained momentum in clinical research and is experiencing a
boom for a variety of applications. There are significant efforts to utilize liquid biopsies in …
boom for a variety of applications. There are significant efforts to utilize liquid biopsies in …
Extracellular microvesicles/exosomes: discovery, disbelief, acceptance, and the future?
MZ Ratajczak, J Ratajczak - Leukemia, 2020 - nature.com
There are concepts in science that need time to overcome initial disbelief before finally
arriving at the moment when they are embraced by the research community. One of these …
arriving at the moment when they are embraced by the research community. One of these …
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
C Théry, KW Witwer, E Aikawa… - Journal of …, 2018 - Wiley Online Library
The last decade has seen a sharp increase in the number of scientific publications
describing physiological and pathological functions of extracellular vesicles (EVs), a …
describing physiological and pathological functions of extracellular vesicles (EVs), a …
Exosomes: Therapy delivery tools and biomarkers of diseases
L Barile, G Vassalli - Pharmacology & therapeutics, 2017 - Elsevier
Virtually all cells in the organism secrete extracellular vesicles (EVs), a heterogeneous
population of lipid bilayer membrane-enclosed vesicles that transport and deliver payloads …
population of lipid bilayer membrane-enclosed vesicles that transport and deliver payloads …
The biology and function of exosomes in cancer
R Kalluri - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
Humans circulate quadrillions of exosomes at all times. Exosomes are a class of
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …
Extracellular vesicles in angiogenesis
D Todorova, S Simoncini, R Lacroix, F Sabatier… - Circulation …, 2017 - Am Heart Assoc
During the past decade, extracellular vesicles (EVs), which include apoptotic bodies,
microvesicles, and exosomes, have emerged as important players in cell-to-cell …
microvesicles, and exosomes, have emerged as important players in cell-to-cell …
Modification of extracellular vesicles by fusion with liposomes for the design of personalized biogenic drug delivery systems
Extracellular vesicles (EVs) are recognized as nature's own carriers to transport
macromolecules throughout the body. Hijacking this endogenous communication system …
macromolecules throughout the body. Hijacking this endogenous communication system …
Re-engineering extracellular vesicles as smart nanoscale therapeutics
In the past decade, extracellular vesicles (EVs) have emerged as a key cell-free strategy for
the treatment of a range of pathologies, including cancer, myocardial infarction, and …
the treatment of a range of pathologies, including cancer, myocardial infarction, and …