Chitosan in nasal delivery systems for therapeutic drugs

L Casettari, L Illum - Journal of Controlled Release, 2014 - Elsevier
There is an obvious need for efficient and safe nasal absorption enhancers for the
development of therapeutically efficacious nasal products for small hydrophilic drugs …

[HTML][HTML] Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applications

TK Giri, A Thakur, A Alexander, H Badwaik… - … Pharmaceutica Sinica B, 2012 - Elsevier
Chitosan, a natural cationic polysaccharide, is prepared industrially by the hydrolysis of the
aminoacetyl groups of chitin, a naturally available marine polymer. Chitosan is a non-toxic …

Nasal drug delivery in humans

C Bitter, K Suter-Zimmermann, C Surber - Topical Applications and the …, 2011 - karger.com
Intranasal administration is an attractive option for local and systemic delivery of many
therapeutic agents. The nasal mucosa is–compared to other mucosae–easily accessible …

Nasal-nanotechnology: revolution for efficient therapeutics delivery

A Kumar, AN Pandey, SK Jain - Drug delivery, 2016 - Taylor & Francis
Context: In recent years, nanotechnology-based delivery systems have gained interest to
overcome the problems of restricted absorption of therapeutic agents from the nasal cavity …

Spray dried powders for nasal delivery: Process and formulation considerations

P Henriques, A Fortuna, S Doktorovová - European Journal of …, 2022 - Elsevier
Powders for nasal delivery have been recognized as advantageous dosage forms over
liquids due to increased stability and residence time on nasal mucosa, with improved …

Solid microparticles based on chitosan or methyl-β-cyclodextrin: A first formulative approach to increase the nose-to-brain transport of deferoxamine mesylate

G Rassu, E Soddu, M Cossu, A Brundu, G Cerri… - Journal of controlled …, 2015 - Elsevier
We propose the formulation and characterization of solid microparticles as nasal drug
delivery systems able to increase the nose-to-brain transport of deferoxamine mesylate …

[图书][B] Chitin and chitosan derivatives: advances in drug discovery and developments

SK Kim - 2013 - books.google.com
A natural long-chain polymer, chitin is the main component of the cell walls of fungi, the
exoskeletons of arthropods (including crustaceans and insects), the radulas of mollusks, and …

Chitosan nanoparticles for gastroesophageal reflux disease treatment

Y Herdiana - Polymers, 2023 - mdpi.com
Gastroesophageal Reflux Disease (GERD) is a chronic ailment that results from the
backward flow of stomach acid into the esophagus, causing heartburn and acid …

Biomedical applications of sheep models: from asthma to vaccines

JPY Scheerlinck, KJ Snibson, VM Bowles… - Trends in …, 2008 - cell.com
Although rodent models are very popular for scientific studies, it is becoming more evident
that large animal models can provide unique opportunities for biomedical research. Sheep …

Formulation and characterization of nanoemulsion-based drug delivery system of risperidone

M Kumar, K Pathak, A Misra - Drug development and industrial …, 2009 - Taylor & Francis
Risperidone nanoemulsion (NE) and mucoadhesive NE formulations were successfully
prepared by the spontaneous emulsification method (titration method) using Capmul MCM …