The potential relevance of long non-coding RNAs in colorectal cancer pathogenesis and treatment: a review focus on signaling pathways

AS Doghish, MB Zaki, MG Eldeib, AF Radwan… - … -Research and Practice, 2024 - Elsevier
Colorectal cancer (CRC) is one of the most frequent cancers in incidence and mortality.
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …

An intelligent DNA nanorobot for detection of MiRNAs cancer biomarkers using molecular programming to fabricate a logic-responsive hybrid nanostructure

A Mirzaiebadizi, H Ravan, S Dabiri… - Bioprocess and …, 2022 - Springer
Herein, we designed a DNA framework-based intelligent nanorobot using toehold-mediated
strand displacement reaction-based molecular programming and logic gate operation for the …

Emerging role of non-coding RNAs in the regulation of KRAS

S Ghafouri-Fard, Z Shirvani-Farsani, BM Hussen… - Cancer cell …, 2022 - Springer
The Kirsten ras oncogene KRAS is a member of the small GTPase superfamily participating
in the RAS/MAPK pathway. A single amino acid substitution in KRAS gene has been shown …

Upregulation of hsa_circ_0004812 promotes COVID‐19 cytokine storm via hsa‐miR‐1287‐5p/IL6R, RIG‐I axis

E Mohammadisoleimani, Z Firoozi… - Journal of clinical …, 2022 - Wiley Online Library
Background SARS‐CoV‐2 is one of the most contagious viruses in the Coronaviridae (CoV)
family, which has become a pandemic. The aim of this study is to understand more about the …

Simultaneous analysis of MLH1, MSH2, MSH6, PMS2 and KRAS in patients with gastric and colon cancer using stochastic sensors

DC Gheorghe, RI Stefan-van Staden, F Pogacean… - Chemosensors, 2022 - mdpi.com
Two stochastic sensors were characterized and validated for the molecular identification and
quantification of MLH1, MSH2, MSH6, PMS2 and KRAS in biological samples using two …

Glycosyltransferase-related long non-coding RNA signature predicts the prognosis of colon adenocarcinoma

J Zhang, Y Wu, J Mu, D Xin, L Wang, Y Fan… - Frontiers in …, 2022 - frontiersin.org
Purpose Colon adenocarcinoma (COAD) is the most common type of colorectal cancer
(CRC) and is associated with poor prognosis. Emerging evidence has demonstrated that …

[PDF][PDF] Identification of lncRNAs expression and their regulatory networks associated with development and growth of skeletal muscle in sheep using RNA-Seq

SB Betti, M Tahmoorespur… - Agriculture and Natural …, 2022 - researchgate.net
Objectives: To identify the genes regulated by long non-coding RNAs (lncRNAs) that are
effective in sheep skeletal muscle growth and development. Materials & Methods: In total …

PROTAC and Molecular Glue Degraders of the Oncogenic RNA Binding Protein Lin28

A Kashkush, J Furth‐Lavi, J Hodon… - Macromolecular …, 2024 - Wiley Online Library
The interaction between proteins and RNA is crucial for regulating gene expression, with
dysregulation often linked to diseases such as cancer. The RNA‐binding protein (RBP) …

Targeting KRAS in gynecological malignancies

Y Peng, Q Yang - The FASEB Journal, 2024 - Wiley Online Library
Cervical, endometrial, and ovarian cancers stand prominently as the leading gynecological
malignancies of the female reproductive system. The conventional therapeutic modalities for …

Alternative Splicing Novel lncRNAs and Their Target Genes in Ovine Skeletal Muscles

SB Betti, M Tahmoorespur… - Journal of Cell and …, 2022 - jcmr.um.ac.ir
Long non-coding RNAs (lncRNAs) compose a plentiful category of transcripts that have
gained increasing importance because of their roles in different biological processes …