[HTML][HTML] Vascular protection afforded by zinc supplementation in human coronary artery smooth muscle cells mediated by NRF2 signaling under hypoxia …
F Yang, MJ Smith, A Griffiths, A Morrell, SJ Chapple… - Redox biology, 2023 - Elsevier
Zinc (Zn) has antioxidant, anti-inflammatory and anti-proliferative actions, with Zn
dysregulation associated with coronary ischemia/reperfusion injury and smooth muscle cell …
dysregulation associated with coronary ischemia/reperfusion injury and smooth muscle cell …
Modern optical approaches in redox biology: Genetically encoded sensors and Raman spectroscopy
AI Kostyuk, DD Rapota, KI Morozova… - Free Radical Biology …, 2024 - Elsevier
The objective of the current review is to summarize the current state of optical methods in
redox biology. It consists of two parts, the first is dedicated to genetically encoded …
redox biology. It consists of two parts, the first is dedicated to genetically encoded …
Controlling pericellular oxygen tension in cell culture reveals distinct breast cancer responses to low oxygen tensions
Abstract In oxygen (O2)‐controlled cell culture, an indispensable tool in biological research,
it is presumed that the incubator setpoint equals the O2 tension experienced by cells (ie …
it is presumed that the incubator setpoint equals the O2 tension experienced by cells (ie …
[HTML][HTML] Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: effects of NRF2 …
MJ Smith, F Yang, A Griffiths, A Morrell, SJ Chapple… - Redox Biology, 2023 - Elsevier
Zinc is an important component of cellular antioxidant defenses and dysregulation of zinc
homeostasis is a risk factor for coronary heart disease and ischemia/reperfusion injury …
homeostasis is a risk factor for coronary heart disease and ischemia/reperfusion injury …
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx
Z Xiang, P Zhang, C Jia, R Xu, D Cao, Z Xu, T Lu… - Bone Research, 2024 - nature.com
To date, several molecules have been found to facilitate iron influx, while the types of iron
influx channels remain to be elucidated. Here, Piezo1 channel was identified as a key iron …
influx channels remain to be elucidated. Here, Piezo1 channel was identified as a key iron …
Probing subcellular iron availability with genetically encoded nitric oxide biosensors
Cellular iron supply is required for various biochemical processes. Measuring bioavailable
iron in cells aids in obtaining a better understanding of its biochemical activities but is …
iron in cells aids in obtaining a better understanding of its biochemical activities but is …
Visualizing hydrogen peroxide and nitric oxide dynamics in endothelial cells using multispectral imaging under controlled oxygen conditions
The complex interplay between hydrogen peroxide (H 2 O 2) and nitric oxide (NO) in
endothelial cells presents challenges due to technical limitations in simultaneous …
endothelial cells presents challenges due to technical limitations in simultaneous …
Nitric Oxide Sensing by a Blue Fluorescent Protein
C Montali, S Abbruzzetti, A Franzen, G Casini, S Bruno… - Antioxidants, 2022 - mdpi.com
S-Nitrosylation of cysteine residues is an important molecular mechanism for dynamic, post-
translational regulation of several proteins, providing a ubiquitous redox regulation. Cys …
translational regulation of several proteins, providing a ubiquitous redox regulation. Cys …
Visualizing H2O2 and NO in endothelial cells: strategies and pitfalls
The relationship between hydrogen peroxide (H2O2) and nitric oxide (NO) in the
vasculature is multifaceted and remains controversial because the dynamic detection of …
vasculature is multifaceted and remains controversial because the dynamic detection of …
Simultaneous manipulation and imaging of chemogenetically induced hydrogen peroxide in hardly transfectable endothelial cells
E Eroğlu - Cumhuriyet Science Journal, 2022 - acikerisim.medipol.edu.tr
Hydrogen peroxide (H2O2) is a critical signaling molecule in vascular cells, which controls
signaling events, yet it can cause pathological oxidative stress in excess. The lack of …
signaling events, yet it can cause pathological oxidative stress in excess. The lack of …