Interleukin-18 in health and disease
K Yasuda, K Nakanishi, H Tsutsui - International journal of molecular …, 2019 - mdpi.com
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from
anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag …
anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag …
Obesity, fat mass and immune system: role for leptin
V Francisco, J Pino, V Campos-Cabaleiro… - Frontiers in …, 2018 - frontiersin.org
Obesity is an epidemic disease characterized by chronic low-grade inflammation associated
with a dysfunctional fat mass. Adipose tissue is now considered an extremely active …
with a dysfunctional fat mass. Adipose tissue is now considered an extremely active …
[HTML][HTML] Articular cartilage regeneration by activated skeletal stem cells
Osteoarthritis (OA) is a degenerative disease resulting in irreversible, progressive
destruction of articular cartilage. The etiology of OA is complex and involves a variety of …
destruction of articular cartilage. The etiology of OA is complex and involves a variety of …
[HTML][HTML] Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition
Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …
economic dimension. Ageing is characterized by an increase in the concentration of …
Salivary biomarkers: novel noninvasive tools to diagnose chronic inflammation
Several chronic disorders including type 2 diabetes (T2D), obesity, heart disease and
cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early …
cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early …
Unwinding circular RNA's role in inflammatory pulmonary diseases
Circular RNAs (circRNAs) have emerged as pivotal regulators of gene expression and
cellular processes in various physiological and pathological conditions. In recent years …
cellular processes in various physiological and pathological conditions. In recent years …
New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis
H Li, D Wang, Y Yuan, J Min - Arthritis research & therapy, 2017 - Springer
Osteoarthritis (OA) is the most common joint disorder and affects approximately half of the
aged population. Current treatments for OA are largely palliative until the articular cartilage …
aged population. Current treatments for OA are largely palliative until the articular cartilage …
[HTML][HTML] Current advances on the therapeutic potential of pinocembrin: an updated review
Abstract Pinocembrin (5, 7-dihydroxyflavone) is a major flavonoid found in many plants,
fungi and hive products, mainly honey and propolis. Several in vitro and preclinical studies …
fungi and hive products, mainly honey and propolis. Several in vitro and preclinical studies …
Roles of circular RNAs in immune regulation and autoimmune diseases
Z Zhou, B Sun, S Huang, L Zhao - Cell death & disease, 2019 - nature.com
Circular RNAs (circRNAs), as a novel class of endogenously expressed non-coding RNAs
(ncRNAs), have a high stability and often present tissue-specific expression and …
(ncRNAs), have a high stability and often present tissue-specific expression and …
Role of host and pathogen-derived microRNAs in immune regulation during infectious and inflammatory diseases
MicroRNAs (miRNAs, miRs) are short, endogenously initiated, non-coding RNAs that bind to
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …