Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation.
Inflammation is one common and effective physiological event that protects against various …

Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Reduced glutathione (GSH) is an essential non-enzymatic antioxidant in mammalian cells.
GSH can act directly as an antioxidant to protect cells against free radicals and pro-oxidants …

Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

Ischemia‐reperfusion (I/R) is a pathological process that occurs in many organs and
diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Iron is an essential trace metal for almost all organisms, including human; however,
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …

Ferroptosis is a novel regulated cell death pattern discovered when studying the mechanism
of erastin-killing RAS mutant tumor cells in 2012. It is an iron-dependent programmed cell …

Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …

Background Ferroptosis is a novel form of lipid reactive oxygen species and iron dependent
cell death, and it has been shown to be involved in renal tubular injury in diabetic mice. Nrf2 …