[HTML][HTML] The interaction between ferroptosis and inflammatory signaling pathways
Y Chen, ZM Fang, X Yi, X Wei, DS Jiang - Cell death & disease, 2023 - nature.com
Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation.
Inflammation is one common and effective physiological event that protects against various …
Inflammation is one common and effective physiological event that protects against various …
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
The antioxidant glutathione
DA Averill-Bates - Vitamins and hormones, 2023 - Elsevier
Reduced glutathione (GSH) is an essential non-enzymatic antioxidant in mammalian cells.
GSH can act directly as an antioxidant to protect cells against free radicals and pro-oxidants …
GSH can act directly as an antioxidant to protect cells against free radicals and pro-oxidants …
[HTML][HTML] Ferroptosis mechanisms involved in neurodegenerative diseases
CO Reichert, FA de Freitas, J Sampaio-Silva… - International journal of …, 2020 - mdpi.com
Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …
Targeting ferroptosis: pathological mechanism and treatment of ischemia‐reperfusion injury
X Li, N Ma, J Xu, Y Zhang, P Yang, X Su… - Oxidative Medicine …, 2021 - Wiley Online Library
Ischemia‐reperfusion (I/R) is a pathological process that occurs in many organs and
diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion …
diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion …
[HTML][HTML] Oxidative stress in liver pathophysiology and disease
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …
not only arise during metabolic functions but also during the biotransformation of …
[HTML][HTML] Iron homeostasis disorder and Alzheimer's disease
Y Peng, X Chang, M Lang - International journal of molecular sciences, 2021 - mdpi.com
Iron is an essential trace metal for almost all organisms, including human; however,
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …
[HTML][HTML] Ferroptosis and its potential role in human diseases
C Han, Y Liu, R Dai, N Ismail, W Su, B Li - Frontiers in pharmacology, 2020 - frontiersin.org
Ferroptosis is a novel regulated cell death pattern discovered when studying the mechanism
of erastin-killing RAS mutant tumor cells in 2012. It is an iron-dependent programmed cell …
of erastin-killing RAS mutant tumor cells in 2012. It is an iron-dependent programmed cell …
Protective effects of estrogen on cardiovascular disease mediated by oxidative stress
D Xiang, Y Liu, S Zhou, E Zhou… - Oxidative medicine and …, 2021 - Wiley Online Library
Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …
has shown that the incidence of cardiovascular disease in premenopausal women is lower …
Umbelliferone delays the progression of diabetic nephropathy by inhibiting ferroptosis through activation of the Nrf-2/HO-1 pathway
T Jin, C Chen - Food and Chemical Toxicology, 2022 - Elsevier
Background Ferroptosis is a novel form of lipid reactive oxygen species and iron dependent
cell death, and it has been shown to be involved in renal tubular injury in diabetic mice. Nrf2 …
cell death, and it has been shown to be involved in renal tubular injury in diabetic mice. Nrf2 …