The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …

Ghrelin, a gastric-derived acylated peptide, regulates energy homeostasis by transmitting
information about peripheral nutritional status to the brain, and is essential for protecting …

Ghrelin was discovered in 1999 as the endogenous ligand of the growth-hormone
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …

Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …

'Hunger is the best spice'is an old and wise saying that acknowledges the fact that almost
any food tastes better when we are hungry. The neurobiological underpinnings of this lore …

Bariatric surgery induces sustained weight loss and metabolic benefits via notable effects on
the gut–brain axis that lead to alterations in the neuroendocrine regulation of appetite and …

Background: Ghrelin, which is a stomach-derived hormone, increases with fasting and
energy restriction and may influence eating behaviors through brain hedonic reward …

Hormones in the hypothalamus–pituitary–adrenal (HPA) axis mediate many of the bodily
responses to stressors, yet there is no clear relationship between the levels of these …

Growth hormone secretagogue receptor (GHSR) 1a is the only molecularly identified
receptor for ghrelin, mediating ghrelin‐related effects on eating, body weight, and blood …