Adult neurogenesis, a process of generating functional neurons from adult neural
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …

Sphere-forming assays have been widely used to retrospectively identify stem cells based
on their reported capacity to evaluate self-renewal and differentiation at the single-cell level …

Abstract N, N-dimethyltryptamine (DMT) is a component of the ayahuasca brew traditionally
used for ritual and therapeutic purposes across several South American countries. Here, we …

Astrocytes, members of the glial family, interact through the exchange of soluble factors or by
directly contacting neurons and other brain cells, such as microglia and endothelial cells …

Forty years since the initial discovery of neurogenesis in the postnatal rat hippocampus,
investigators have now firmly established that active neurogenesis from neural progenitors …

The subventricular zone (SVZ) is the largest neurogenic niche in the adult mammalian brain.
We found that the brain-enriched microRNA miR-124 is an important regulator of the …

Much excitement has been generated by the identification of adult brain regions harboring
neural stem cells and their continual generation of new neurons throughout life. This is an …

The subventricular zone (SVZ) is a principal source of adult neural stem cells in the rodent
brain, generating thousands of olfactory bulb neurons every day. If the adult human brain …

During an investigation of the mechanisms through which the local environment controls the
fate specification of adult neural stem cells, we discovered that adult astrocytes from …

The adult mammalian brain retains neural stem cells that continually generate new neurons
within two restricted regions: the subventricular zone (SVZ) of the lateral ventricle and the …