The neural crest is a stem/progenitor cell population that contributes to a wide variety of
derivatives, including sensory and autonomic ganglia, cartilage and bone of the face and …

▪ Abstract Early development of the vertebrate skeleton depends on genes that pattern the
distribution and proliferation of cells from cranial neural crest, sclerotomes, and lateral plate …

A clear, engaging writing style, hundreds of full-color images, and new information
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …

Fate-changing transcription factors (TFs) scan chromatin to initiate new genetic programs
during cell differentiation and reprogramming. Yet the protein structure domains that allow …

Directing the fate of human pluripotent stem cells (hPSCs) into different lineages requires
variable starting conditions and components with undefined activities, introducing …

ABSTRACT β-Catenin is a central component of both the cadherin-catenin cell adhesion
complex and the Wnt signaling pathway. We have investigated the role of β-catenin during …

Craniofacial anomalies, and in particular cleft lip and palate, are major human birth defects
with a worldwide frequency of 1 in 700 and substantial clinical impact. A wide range of …

The transcriptional coactivator and integrator p300 and its closely related family member
CBP mediate multiple, signal-dependent transcriptional events. We have generated mice …

Congenital defects of neural tube closure (neural tube defects; NTDs) are among the
commonest and most severe disorders of the fetus and newborn. Disturbance of any of the …

Neural crest cells (NCC) are a transient, embryonic cell population characterized by unusual
migratory ability and developmental plasticity. To annotate and characterize cis-regulatory …