[HTML][HTML] Recent advances in understanding the reversal of gene silencing during X chromosome reactivation

I Talon, A Janiszewski, J Chappell… - Frontiers in Cell and …, 2019 - frontiersin.org
Dosage compensation between XX female and XY male cells is achieved by a process
known as X chromosome inactivation (XCI) in mammals. XCI is initiated early during …

[HTML][HTML] Research advances of polycomb group proteins in regulating mammalian development

Y Li, Y Mo, C Chen, J He, Z Guo - Frontiers in Cell and …, 2024 - frontiersin.org
Polycomb group (PcG) proteins are a subset of epigenetic factors that are highly conserved
throughout evolution. In mammals, PcG proteins can be classified into two muti-proteins …

Visualization of X chromosome reactivation in mouse primordial germ cells in vivo

Y Haramoto, M Sakata, S Kobayashi - Biology Open, 2021 - journals.biologists.com
ABSTRACT X chromosome inactivation (XCI), determined during development, remains
stable after embryonic cell divisions. However, primordial germ cells (PGCs) are exceptions …

Quick validation of genetic quality for conditional alleles in mice

H Nakata, T Hashimoto, A Yoshiki - Genes to Cells, 2021 - Wiley Online Library
Site‐specific conditional inactivation technologies using Cre‐loxP or Flp‐FRT systems are
becoming increasingly important for the elucidation of gene function and disease …