[HTML][HTML] Phenolic acids: Natural versatile molecules with promising therapeutic applications

N Kumar, N Goel - Biotechnology reports, 2019 - Elsevier
Plant phenolics are considered to be a vital human dietary component and exhibit a
tremendous antioxidant activity as well as other health benefits. Epidemiology evidence …

Spontaneously fermented traditional beverages as a source of bioactive compounds: an overview

RB Cuvas-Limon, C Nobre, M Cruz… - Critical reviews in …, 2021 - Taylor & Francis
Fermented food has been present throughout history, since fermentation not only helps
preserving food, but also provides specific organoleptic characteristics typically associated …

Using integrated computational approaches to identify safe and rapid treatment for SARS-CoV-2

K Al-Khafaji, D Al-Duhaidahawi… - Journal of Biomolecular …, 2021 - Taylor & Francis
SARS-CoV-2 is a new generation of coronavirus, which was first determined in Wuhan,
China, in December 2019. So far, however, there no effective treatment has been found to …

Extraction, characterization of polyphenols from certain medicinal plants and evaluation of their antioxidant, antitumor, antidiabetic, antimicrobial properties, and …

A Mueed, S Shibli, DA Al-Quwaie, MF Ashkan… - Frontiers in …, 2023 - frontiersin.org
Introduction Dietary medicinal plants are among the most sought-after topics in alternative
medicine today due to their preventive and healing properties against many diseases. Aim …

Molecular dynamics simulation, free energy landscape and binding free energy computations in exploration the anti-invasive activity of amygdalin against metastasis

K Al-Khafaji, TT Tok - Computer Methods and Programs in Biomedicine, 2020 - Elsevier
Background and objective Historically, amygdalin has been used as alternative medicine or
in vitro and in vivo studies, but no single study exists which discusses the structural …

Identification of potent inhibitors of HDAC2 from herbal products for the treatment of colon cancer: Molecular docking, molecular dynamics simulation, MM/GBSA …

M Khanal, A Acharya, R Maharjan, K Gyawali… - Plos one, 2024 - journals.plos.org
The histone deacetylase 2 (HDAC2), an enzyme involved in gene regulation, is a potent
drug target for the treatment of colon cancer. Phytocompounds having anticancer properties …

In silico protein engineering shows that novel mutations affecting NAD+ binding sites may improve phosphite dehydrogenase stability and activity

S Baammi, R Daoud, A El Allali - Scientific Reports, 2023 - nature.com
Pseudomonas stutzeri phosphite dehydrogenase (PTDH) catalyzes the oxidation of
phosphite to phosphate in the presence of NAD, resulting in the formation of NADH. The …

3D-printed solid phase microextraction fiber based on Co-Al layered double hydroxide nanosheets; application in determination of phenolic acids in fruit juice samples

H Rezaei, AA Matin - Food Chemistry, 2024 - Elsevier
Abstract 3D printing technology has attracted great attention in various fields of science and
technology. Application of this technology in manufacturing analytical tools is developing …

Heterocyclic compounds: importance in anticancer drug discovery

N Kumar, N Goel - Anti-Cancer Agents in Medicinal Chemistry …, 2022 - benthamdirect.com
Cancer, a crucial global health problem, is characterized by abnormal cell division and
uncontrolled growth. According to WHO, cancer is the second leading cause of global …

Natural products as potential lead compounds for drug discovery against SARS-CoV-2

OT Ebob, SB Babiaka, F Ntie-Kang - Natural products and bioprospecting, 2021 - Springer
For the past 2 years, the coronavirus responsible for the COVID-19 infection has become a
world pandemic, ruining the lives and economies of several nations in the world. This has …