Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

[HTML][HTML] Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies

H Lin, Y Yu, L Zhu, N Lai, L Zhang, Y Guo, X Lin… - Redox Biology, 2023 - Elsevier
Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy

Y Zhang, J Fang, S Ye, Y Zhao, A Wang, Q Mao… - Nature …, 2022 - nature.com
Hydrogen sulfide (H2S) as an important biological gasotransmitter plays a pivotal role in
many physiological and pathological processes. The sensitive and quantitative detection of …

Gut microbiota reinforce host antioxidant capacity via the generation of reactive sulfur species

J Uchiyama, M Akiyama, K Hase, Y Kumagai, YG Kim - Cell Reports, 2022 - cell.com
Gut microbiota act beyond the gastrointestinal tract to regulate the physiology of the host.
However, their contribution to the antioxidant capacity of the host remains largely …

Gut-microbial metabolites, probiotics and their roles in type 2 diabetes

L Zhai, J Wu, YY Lam, HY Kwan, ZX Bian… - International Journal of …, 2021 - mdpi.com
Type 2 diabetes (T2D) is a worldwide prevalent metabolic disorder defined by high blood
glucose levels due to insulin resistance (IR) and impaired insulin secretion. Understanding …

Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species

KG Fosnacht, MD Pluth - Chemical Reviews, 2024 - ACS Publications
Hydrogen sulfide (H2S) is not only a well-established toxic gas but also an important small
molecule bioregulator in all kingdoms of life. In contemporary biology, H2S is often classified …

Protective role of hydrogen sulfide against diabetic cardiomyopathy via alleviating necroptosis

W Gong, S Zhang, Y Chen, J Shen, Y Zheng… - Free Radical Biology …, 2022 - Elsevier
Highlights●H 2 S production was impaired in db/db mice and streptozotocin-induced
diabetic mice.●CSE knockout exacerbated diabetic cardiomyopathy in streptozotocin …

[HTML][HTML] Recent advances on endogenous gasotransmitters in inflammatory dermatological disorders

L Wang, X Xie, B Ke, W Huang, X Jiang, G He - Journal of Advanced …, 2022 - Elsevier
Background Endogenous gasotransmitters are small gaseous mediators that can be
generated endogenously by mammalian organisms. The dysregulation of the …

A novel fluorescent probe for imagining hydrogen sulfide upregulation in acute lung injury

W Su, L Huang, L Zhu, W Lin - Sensors and Actuators B: Chemical, 2022 - Elsevier
Acute lung injury (ALI) is a severe pulmonary inflammatory disease with high morbidity and
mortality, whose pathogenesis and treatment are still under exploration. Hydrogen sulfide (H …

NRF2 activation and downstream effects: focus on Parkinson's disease and brain angiotensin

JA Parga, AI Rodriguez-Perez, M Garcia-Garrote… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are signalling molecules used to regulate cellular
metabolism and homeostasis. However, excessive ROS production causes oxidative stress …