Downregulation of tumor necrosis factor and other proinflammatory biomarkers by polyphenols
Human tumor necrosis factor (TNF), first isolated by our group as an anticancer agent, has
been now shown to be a primary mediator of inflammation. Till today 19 different members of …
been now shown to be a primary mediator of inflammation. Till today 19 different members of …
Therapeutic significance of β-glucuronidase activity and its inhibitors: A review
The emergence of disease and dearth of effective pharmacological agents on most
therapeutic fronts, constitutes a major threat to global public health and man's existence …
therapeutic fronts, constitutes a major threat to global public health and man's existence …
Development of novel pyrazole, imidazo [1, 2-b] pyrazole, and pyrazolo [1, 5-a] pyrimidine derivatives as a new class of COX-2 inhibitors with immunomodulatory …
Searching for new compounds with anti-inflammatory properties is a significant target since
inflammation is a major cause of pain. A series of pyrazole, imidazopyrazolone, and …
inflammation is a major cause of pain. A series of pyrazole, imidazopyrazolone, and …
[HTML][HTML] Evaluation of anti-inflammatory activity of selected medicinal plants used in Indian traditional medication system in vitro as well as in vivo
The present study was carried out to evaluate in vivo and in vitro anti-inflammatory potential
of selected medicinal plants used in Indian traditional medication. The sequentially extracted …
of selected medicinal plants used in Indian traditional medication. The sequentially extracted …
Chemical Characterization and Anti-Inflammatory Activity of Phytoconstituents from Swertia alata
S Bajaj, S Fuloria, V Subramaniyan, DU Meenakshi… - Plants, 2021 - mdpi.com
Swertia alata CB Clarke (Gentianaceae) is a well-reported plant in the traditional system of
medicine. The present study was intended to isolate the phytoconstituents from the ethanolic …
medicine. The present study was intended to isolate the phytoconstituents from the ethanolic …
Curcumin analogues and derivatives with anti-proliferative and anti-inflammatory activity: Structural characteristics and molecular targets
E Chainoglou, D Hadjipavlou-Litina - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Curcumin (Diferuloylmethane) is a natural phenolic compound,
which belongs to the curcuminoid family, presenting pleiotropic activity and low …
which belongs to the curcuminoid family, presenting pleiotropic activity and low …
Synthesis and cytotoxicity evaluation of novel asymmetrical mono-carbonyl analogs of curcumin (AMACs) against Vero, HeLa, and MCF7 Cell Lines
A series of novel asymmetrical mono-carbonyl analogs of curcumin (AMACs) were
synthesized and evaluated for cytotoxic activity using BSLT and MTT assay against Vero …
synthesized and evaluated for cytotoxic activity using BSLT and MTT assay against Vero …
Synthesis, in vitro, in silico and DFT studies of indole curcumin derivatives as potential anticancer agents
The curcumin derivatives were synthesized for the first time using simple starting materials
through a three-component reaction, yielding high purity compounds. The synthesized …
through a three-component reaction, yielding high purity compounds. The synthesized …
Development of antioxidant COX-2 inhibitors as radioprotective agents for radiation therapy—a hypothesis-driven review
M Laube, T Kniess, J Pietzsch - Antioxidants, 2016 - mdpi.com
Radiation therapy (RT) evolved to be a primary treatment modality for cancer patients.
Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side …
Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side …
Screening of curcumin‐derived isoxazole, pyrazoles, and pyrimidines for their anti‐inflammatory, antinociceptive, and cyclooxygenase‐2 inhibition
Curcumin has shown pharmacological properties against different phenotypes of various
disease models. Different synthetic routes have been employed to develop its numerous …
disease models. Different synthetic routes have been employed to develop its numerous …