For a number of years, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases
(NOX) was synonymous with NOX2/gp91phox and was considered to be a peculiarity of …

Nanotechnology is a rapidly developing field in the 21 st century, and the commercial use of
nanomaterials for novel applications is increasing exponentially. To date, the scientific basis …

Microglia, the resident immune cells of the brain, rapidly change states in response to their
environment, but we lack molecular and functional signatures of different microglial …

Traumatic brain injury (TBI) is a major cause of death in the young age group and leads to
persisting neurological impairment in many of its victims. It may result in permanent …

In senescent cells, a DNA damage response drives not only irreversible loss of replicative
capacity but also production and secretion of reactive oxygen species (ROS) and bioactive …

The brain is a metabolically active organ exhibiting high oxygen consumption and robust
production of reactive oxygen species (ROS). The large amounts of ROS are kept in check …

Although oxidants clearly possess the capacity to behave in a random and destructive
fashion, growing evidence suggests that in many instances the production of reactive …

Aging is an inherently complex process that is manifested within an organism at genetic,
molecular, cellular, organ, and system levels. Although the fundamental mechanisms are …

Abstract Alzheimer's disease (AD), the most common chronic and progressive
neurodegenerative disorder, is characterized by extracellular deposits of amyloid β-peptides …

This article reviews the reported phytochemical, pharmacological and toxicological
properties of Hibiscus sabdariffa L.(English: roselle, red sorrel; Arabic: karkade), the calyces …