Cell migration is an adaptive process that depends on and responds to physical and
molecular triggers. Moving cells sense and respond to tissue mechanics and induce …

Collagen is a major component in a wide range of drug delivery systems and biomaterial
applications. Its basic physical and structural properties, together with its low …

Confocal laser endomicroscopy (pCLE) provides real-time histologic imaging of human
tissues at a depth of 60–70 μm during endoscopy. pCLE of the extrahepatic bile duct after …

The ability to respond to injury with tissue repair is a fundamental property of all multicellular
organisms. The extracellular matrix (ECM), composed of fibrillar collagens as well as a …

Significance: With an aging population leading to an increase in diabetes and associated
cutaneous wounds, there is a pressing clinical need to improve wound-healing therapies …

Cell metabolism is strongly influenced by mechano-environment. We show here that a
fraction of kindlin-2 localizes to mitochondria and interacts with pyrroline-5-carboxylate …

Abnormal architectures of collagen fibers in the extracellular matrix (ECM) are hallmarks of
many invasive diseases, including cancer. Targeting specific stages of collagen assembly in …

The papillary dermis of human skin is responsible for its biomechanical properties and for
supply of epidermis with chemicals. Dermis is mainly composed of structural protein …

In the drug development process, the accurate prediction of drug efficacy and toxicity is
important in order to reduce the cost, labor, and effort involved. For this purpose …

Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …