ATP citrate lyase: A central metabolic enzyme in cancer
ACLY links energy metabolism provided by catabolic pathways to biosynthesis. ACLY,
which has been found to be overexpressed in many cancers, converts citrate into acetyl-CoA …
which has been found to be overexpressed in many cancers, converts citrate into acetyl-CoA …
A comprehensive scientific overview of Garcinia cambogia
The fruit rind of Garcinia gummi-gutta, commonly known as Garcinia cambogia (syn.), is
extensively used traditionally as a flavourant in fish curries due to its sharp sour taste …
extensively used traditionally as a flavourant in fish curries due to its sharp sour taste …
[HTML][HTML] Caloric restriction mimetics enhance anticancer immunosurveillance
Caloric restriction mimetics (CRMs) mimic the biochemical effects of nutrient deprivation by
reducing lysine acetylation of cellular proteins, thus triggering autophagy. Treatment with the …
reducing lysine acetylation of cellular proteins, thus triggering autophagy. Treatment with the …
Fatty acid metabolism reprogramming in ccRCC: mechanisms and potential targets
Lipid droplet formation is a defining histological feature in clear-cell renal cell carcinoma
(ccRCC) but the underlying mechanisms and importance of this biological behaviour have …
(ccRCC) but the underlying mechanisms and importance of this biological behaviour have …
Updates on Antiobesity Effect of Garcinia Origin (−)‐HCA
Garcinia is a plant under the family of Clusiaceae that is commonly used as a flavouring
agent. Various phytochemicals including flavonoids and organic acid have been identified in …
agent. Various phytochemicals including flavonoids and organic acid have been identified in …
Anti-obesity effect of extract from fermented Curcuma longa L. through regulation of adipogenesis and lipolysis pathway in high-fat diet-induced obese rats
JH Kim, OK Kim, HG Yoon, J Park, Y You… - Food & nutrition …, 2016 - Taylor & Francis
Background Even though Curcuma longa L. possesses various biological activities, it has
strong flavor and taste, which decrease consumer palatability and limit industrial …
strong flavor and taste, which decrease consumer palatability and limit industrial …
Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl …
X Shi, X Chen, X Li, X Lan, C Zhao, S Liu, H Huang… - Clinical Cancer …, 2014 - AACR
Purpose: Chronic myelogenous leukemia (CML) is characterized by the constitutive
activation of Bcr-Abl tyrosine kinase. Bcr-Abl-T315I is the predominant mutation that causes …
activation of Bcr-Abl tyrosine kinase. Bcr-Abl-T315I is the predominant mutation that causes …
ATP-citrate lyase epigenetically potentiates oxidative phosphorylation to promote melanoma growth and adaptive resistance to MAPK inhibition
Purpose: Enhanced lipogenesis and mitochondrial function are two critical metabolic
characteristics in melanoma, but their crosstalk involved in tumor biology and targeted …
characteristics in melanoma, but their crosstalk involved in tumor biology and targeted …
Nutrition supplements to stimulate lipolysis: a review in relation to endurance exercise capacity
Athletes make great efforts to increase their endurance capacity in many ways. Using
nutrition supplements for stimulating lipolysis is one such strategy to improve endurance …
nutrition supplements for stimulating lipolysis is one such strategy to improve endurance …
Effectiveness of herbal medicines for weight loss: A systematic review and meta‐analysis of randomized controlled trials
Aim To update the available evidence on the efficacy and safety of complementary
medicines to assist in weight loss by conducting a systematic review and meta‐analysis of …
medicines to assist in weight loss by conducting a systematic review and meta‐analysis of …