AMP-activated protein kinase (AMPK) has a major role in the modulation of energy balance.
AMPK is activated in conditions of low energy, increasing energy production and reducing …

Complex multicellular organisms require a coordinated response from multiple tissues to
maintain whole-body homeostasis in the face of energetic stressors such as fasting, cold …

AMP-activated protein kinase (AMPK) is the downstream component of a kinase cascade
that acts as a gauge of cellular energy levels. Over the last few years, accumulating …

The human solute carrier (SLC) transporters are important targets for drug development.
Structure-based drug discovery for SLC transporters requires the description of their …

Reduced expression of the Indy (I'm Not Dead, Yet) gene in D. melanogaster and its
homolog in C. elegans prolongs life span and in D. melanogaster augments mitochondrial …

A comprehensive understanding of the key microenvironmental signals regulating bone
regeneration is pivotal for the effective design of bioinspired orthopedic materials. Here, we …

The hypothalamus plays a crucial role in the regulation of food intake and energy
expenditure. One of the main regulatory factors within the hypothalamus is AMP-activated …

It is widely accepted that thyroid cancer is strongly determined by the individual genetic
background. In this regard, it is expected that sporadic thyroid cancer is the result of multiple …

The present study was conducted to evaluate the analgesic effects of po, ip, or icv
administration of ellagic acid (EA), and investigate the possible mechanisms underlying the …

Objective The goal of this study was to determine the presence early of markers of
endoplasmic reticulum stress (ERS) and insulin resistance in the offspring from dams fed …