Pancreatic ductal adenocarcinoma (PDAC) features a prominent stromal microenvironment
with remarkable cellular and spatial heterogeneity that meaningfully impacts disease …

The CCR7 chemokine axis is comprised of chemokine ligand 21 (CCL21) and chemokine
ligand 19 (CCL19) acting on chemokine receptor 7 (CCR7). This axis plays two important …

Chemokine networks regulate a variety of cellular, physiological, and immune processes.
These normal functions can become appropriated by cancer cells to facilitate a more …

Background Tumor-induced lymphangiogenesis facilitates breast cancer progression by
generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph …

The relationship between gut microbiota and type 2 diabetes mellitus (T2DM) has drawn
increasing attention, and the benefits of various treatment strategies, including nutrition …

CC chemokine receptor 7 (CCR7) was one of the first two chemokine receptors that were
found to be upregulated in breast cancers. Chemokine receptors promote chemotaxis of …

Although current opinion indicates that tumor-induced lymphangiogenesis plays a key role
in promoting the initial spread of malignant tumors, the mechanism that underlies lymphatic …

Tibial dyschondroplasia (TD) is the most-prevalent leg disorder in fast-growing chickens; it is
intractable and characterized by abnormal endochondral bone formation of proximal tibial …

Obesity is a most prevalent human health problem. Several studies showed that appropriate
modulation of gut microbiota could help reshape the metabolic profile of obese individuals …

This review summarizes current knowledge of the biology, pathology and clinical
understanding of lymphatic invasion and metastasis in pancreatic cancer. We discuss the …