The histone demethylase LSD1 regulates B cell proliferation and plasmablast differentiation

RR Haines, BG Barwick, CD Scharer… - The Journal of …, 2018 - journals.aai.org
B cells undergo epigenetic remodeling as they differentiate into Ab-secreting cells (ASC).
LSD1 is a histone demethylase known to decommission active enhancers and cooperate …

Plasma Proteomic Signature Predicts Myeloid Neoplasm Risk

D Tran, JS Beeler, J Liu, B Wiley, ICC Chan, Z Xin… - Clinical Cancer …, 2024 - AACR
Purpose: Clonal hematopoiesis (CH) is thought to be the origin of myeloid neoplasms (MN).
Yet, our understanding of the mechanisms driving CH progression to MN and clinical risk …

AMIGO2 attenuates innate cisplatin sensitivity by suppression of GSDME‐conferred pyroptosis in non‐small cell lung cancer

L Chen, S Lin, Y Xie, X Tan, B Xiong… - Journal of Cellular …, 2023 - Wiley Online Library
Non‐small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer.
Cisplatin is commonly used in the treatment of many malignant tumours including NSCLC …

Regulation of neurogenesis in mouse brain by HMGB1

X Zhao, A Rouhiainen, Z Li, S Guo, H Rauvala - Cells, 2020 - mdpi.com
The High Mobility Group Box 1 (HMGB1) is the most abundant nuclear nonhistone protein
that is involved in transcription regulation. In addition, HMGB1 has previously been found as …

Role of AMIGO2 in cancer progression: Novel insights

Z Tian, D Zhou, R Jiang, B Zhou - Oncology Letters, 2024 - spandidos-publications.com
Adhesion molecule with IgG‑like domain 2 (AMIGO2) is a novel scaffold protein initially
identified in cerebellar granule neurons, and inhibits apoptosis of neurons. It is also widely …

AMIGO2 as a novel indicator of liver metastasis in patients with colorectal cancer

A Tanio, H Saito, M Amisaki, K Hara… - Oncology …, 2021 - spandidos-publications.com
Our previous study showed that adhesion molecule with immunoglobulin like domain 2
(AMIGO2) is a pivotal driver gene of liver metastasis via regulating tumor cell adhesion to …

[HTML][HTML] Integrated analysis reveals prognostic value and progression-related role of AMIGO2 in prostate cancer

Z Han, Y Feng, Y Deng, Z Tang, S Cai… - Translational …, 2022 - ncbi.nlm.nih.gov
Background Even though emerging studies supplied evidence that Adhesion Molecule with
Ig Like Domain family 2 (AMIGO2) plays a critical role in numerous cancers, comprehensive …

Adhesion molecule Amigo2 is involved in the fasciculation process of the fasciculus retroflexus

V Company, R Murcia‐Ramón… - Developmental …, 2022 - Wiley Online Library
Background The fasciculus retroflexus is the prominent efferent pathway from the habenular
complex. Medial habenular axons form a core packet whereas lateral habenular axons …

[HTML][HTML] New insights into development of the habenular complex and the fasciculus retroflexus

E Puelles Martínez de la Torre, D Echevarria Aza - 2021 - dialnet.unirioja.es
La Habénula es un complejo neuronal diencefálico ubicado en la parte más dorsal del
prosómero talámico. Esta población neuronal está involucrada en el sistema límbico, y su …

AMIGO2 promotes proliferation of nasopharyngeal carcinoma cells by activating the PI3K/AKT/mTOR signaling pathway.

YE Wangzhong, XU Yuanji, YE Yunbin… - Chinese Journal of …, 2020 - search.ebscohost.com
Objective: To explore the role of adhesion molecule with Ig like domain 2 (AMIGO2) in the
proliferation of nasopharyngeal carcinoma (NPC) cells and its mechanisms. Methods: A total …