Background: The central vein sign (CVS) is a radiological feature proposed as a multiple
sclerosis (MS) imaging biomarker able to accurately differentiate MS from other white matter …

Focal lesions in both white and gray matter are characteristic of multiple sclerosis (MS).
Histopathological studies have helped define the main underlying pathological processes …

Background and Objectives The central vein sign (CVS), a central linear hypointensity within
lesions on T2*-weighted imaging, has been established as a sensitive and specific …

Differentiating multiple sclerosis (MS) from other relapsing inflammatory autoimmune
diseases of the central nervous system such as neuromyelitis optica spectrum disorder …

Rationale and objectives Susceptibility-weighted imaging (SWI) is a valuable method in the
diagnosis of multiple sclerosis (MS). SWI can show diagnostic biomarkers and also …

Background: Cerebrospinal fluid (CSF) oligoclonal bands (OCB) are a diagnostic biomarker
in multiple sclerosis (MS). The central vein sign (CVS) is an imaging biomarker for MS that …

Background Diagnosis of multiple sclerosis (MS) frequently relies on MRI dissemination in
time (DIT) and space (DIS), as codified in 2017 McDonald criteria (McD 2017). The central …

Various detailed models of cerebral circulation have been proposed, recently fostered by the
hypothesized relationship between extracranial venous drainage impairment and …

AIM This study aimed to summarise and analyse the magnetic resonance imaging (MRI)
characteristics of patients with myelin oligodendrocyte glycoprotein-immunoglobulin G …

The presence of central nervous system lesions fulfilling the criteria of dissemination in
space and time on MRI leads to the diagnosis of a radiologically isolated syndrome (RIS) …