[HTML][HTML] Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review
This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …
Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function
The purpose of this paper is to provide an integrative review and offer novel insights
regarding human research with classic psychedelics (classic hallucinogens), which are …
regarding human research with classic psychedelics (classic hallucinogens), which are …
Hallucinogens in mental health: preclinical and clinical studies on LSD, psilocybin, MDMA, and ketamine
A revamped interest in the study of hallucinogens has recently emerged, especially with
regard to their potential application in the treatment of psychiatric disorders. In the last …
regard to their potential application in the treatment of psychiatric disorders. In the last …
Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
[HTML][HTML] The fabric of meaning and subjective effects in LSD-induced states depend on serotonin 2A receptor activation
KH Preller, M Herdener, T Pokorny, A Planzer… - Current Biology, 2017 - cell.com
A core aspect of the human self is the attribution of personal relevance to everyday stimuli
enabling us to experience our environment as meaningful [1]. However, abnormalities in the …
enabling us to experience our environment as meaningful [1]. However, abnormalities in the …
Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline
D De Gregorio, A Inserra, JP Enns… - …, 2022 - nature.com
Lysergic acid diethylamide (LSD) is a serotonergic psychedelic compound receiving
increasing interest due to putative anxiolytic and antidepressant properties. However, the …
increasing interest due to putative anxiolytic and antidepressant properties. However, the …
Ketamine and serotonergic psychedelics: an update on the mechanisms and biosignatures underlying rapid-acting antidepressant treatment
The discovery of ketamine as a rapid-acting antidepressant spurred significant research to
understand its underlying mechanisms of action and to identify other novel compounds that …
understand its underlying mechanisms of action and to identify other novel compounds that …
Psychedelic drugs in biomedicine
Psychedelic drugs, such as lysergic acid diethylamide (LSD), mescaline, and psilocybin,
exert profound effects on brain and behavior. After decades of difficulties in studying these …
exert profound effects on brain and behavior. After decades of difficulties in studying these …
Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity
Renewed interest in classic psychedelics as treatments for psychiatric disorders warrants a
deeper understanding of their neural mechanisms. Single, high doses of psychedelic drugs …
deeper understanding of their neural mechanisms. Single, high doses of psychedelic drugs …
A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers
JG Ramaekers, N Hutten, NL Mason… - Journal of …, 2021 - journals.sagepub.com
Background: Lysergic acid diethylamide (LSD) is an ergot alkaloid derivative with
psychedelic properties that has been implicated in the management of persistent pain …
psychedelic properties that has been implicated in the management of persistent pain …