Mesenchymal stem cells (MSC) have been considered the promising candidates for the
regenerative and personalized medicine due to their self-renewal potential, multilineage …

Wound healing, cardiac fibrosis, and infarct scar development, while possessing distinct
features, share a number of key functional similarities, including extracellular matrix …

Hypoxia of local tissue occurs during the scar formation; however, the degree of ischemia
and hypoxia in the central areas of keloids is more serious than those in normal scars …

Impaired wound healing represents an enormous clinical and financial problem for
companion animals and humans alike. Unfortunately, most models used to study healing …

Background Adipose-derived stem cells (ASCs) are being increasingly recognized for their
potential to promote tissue regeneration and wound healing. These effects appear to be …

The formation of vasculature is essential for tissue maintenance and regeneration. During
development, the vasculature forms via the dual processes of vasculogenesis and …

Periostin, a secreted extracellular matrix protein, is involved in the wound healing and
pathological process of various human cancers. Keloid scars are fibroproliferative tumor-like …

The ubiquitin proteasome system (UPS) is a highly conserved way to regulate protein
turnover in cells. The UPS hydrolyzes and destroys variant or misfolded proteins and finely …

Distal extremity wounds are a significant clinical problem in horses and humans and may
benefit from mesenchymal stem cell (MSC) therapy. This study evaluated the effects of direct …

Simple Summary The main target of mesenchymal stem cell therapy in horses has long
been the locomotor system, because these athletic animals commonly suffer from tendon …