Introduction: Current research efforts focused on the design and evaluation of drug delivery
systems that are easy to administer require decreased administration frequency, and …

methods. Melanin content in ocular tissues of both the strains was determined by sodium
hydroxide solubilization method. The affinity of celecoxib to synthetic and natural melanin …

Introduction: Current drug delivery research is focused on improving the efficacy of drug
delivery systems, with emphasis on precise targeting, accurate dose delivery, strategies for …

Objectives The use of L-carnosine as an excipient in topical ophthalmic formulations
containing gellan gum, a carbohydrate polymer with in-situ gelling properties upon mixing …

PF-00337210 is a potent, selective small molecule inhibitor of VEGFRs and has been under
consideration for the treatment of age-related macular degeneration. An ophthalmic solution …

With the rapid increase in the elderly population, the number of Americans afflicted with
vision impairment due to ocular disease is projected to rise substantially by the year 2020 …

This chapter strives to provide an understanding of the overall drug product approval
process and highlights the key points that a sponsor needs to focus on in order to …

Sustained transscleral retinal corticosteroid delivery is an alternative to intravitreal injections
for treating back of the eye disorders in order to minimize injection and drug associated side …

Retinal disorders such as age related macular degeneration and diabetic retinopathy are
the leading causes of blindness. Traditional approaches in treating these diseases delay the …

La aprobación de los inhibidores del factor de crecimiento endotelial vascular (VEGF)
Macugen®(2004) y Lucentis®(2006) por la Administración estadounidense de Fármacos y …