Control of mRNA translation plays a crucial role in the regulation of gene expression and is
critical for cellular homeostasis. Dysregulation of translation initiation factors has been …

Here we discuss the function of eukaryotic initiation factor 6 (eIF6; Tif6 in yeast). eIF6 binds
60S ribosomal subunits and blocks their joining to 40S. In this context, we propose that eIF6 …

Accumulating evidence has identified long noncoding RNAs (lncRNAs) as regulators in
tumor progression and development. Here, we elucidated the function and possible …

Simple Summary Xenopus laevis is an anuran amphibian that has been used for decades
as the principal vertebrate model to study embryonic development. Among the advantages …

Colorectal cancer (CRC) is the third most common cause of cancer related death worldwide.
Furthermore, with more than 1.2 million cases registered per year, it constitutes the third …

Copper is an essential micronutrient but its excess in the dietary can be toxic. Both copper
deficiency and abundance can occur in natural conditions and can lead to pathological …

Okadaic acid (OA) is a principal diarrhetic shellfish poisoning toxin produced by marine
dinoflagellates. This study compared protein profiles of mice small intestines at four time …

Abstract Eukaryotic initiation factor 6 (eIF6) is necessary for ribosome biogenesis and
translation, but eIF6 has been poorly elucidated in insects. Phylogenetic analysis …

A growing body of evidence indicates that protein factors controlling translation play an
important role in tumorigenesis. The protein known as eIF6 is a ribosome anti-association …

Background: Neural crest formation is one of the fundamental processes in the early stages
of embryonic development in vertebrates. This transient and multipotent embryonic cell …