The formyl peptide receptors (FPRs) are G protein-coupled receptors that transduce
chemotactic signals in phagocytes and mediate host-defense as well as inflammatory …

Formyl peptide receptors (FPRs) are a small group of seven-transmembrane domain, G
protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes …

Formyl-peptide receptors (FPRs) recognize bacterial and mitochondrial formylated peptides
as well as endogenous non-formylated peptides and even lipids. FPRs are expressed on …

The formyl peptide receptor (FPR) family is involved in host defence against pathogens, but
also in sensing internal molecules that may constitute signals of cellular dysfunction. It …

Alzheimer's disease (AD) is characterized by overproduction of β amyloid peptides in the
brain with progressive loss of neuronal cells. The 42-aa form of the β amyloid peptide (Aβ …

FPR and FPRL1 belong to the seven-transmembrane, G protein-coupled chemoattractant
receptor superfamily. Because of their capacity to interact with bacterial chemotactic …

Leukocyte recruitment to sites of inflammation and infection is dependent on the presence of
a gradient of locally produced chemotactic factors. This review is focused on current …

Ischaemia–reperfusion (I/R) injury is a common feature of several diseases associated with
high morbidity and mortality, such as stroke and myocardial infarction. The damaged tissue …

Cardiovascular disease (CVD) continues to be the leading cause of death in the world.
Increased inflammation and an enhanced thrombotic milieu represent two major …

Application of highly active antiretroviral drugs (ARDs) effectively reduces morbidity and
mortality in HIV-infected individuals. However, the emergence of multiple drug-resistant …