Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

A genomic overview of the population structure of Salmonella

NF Alikhan, Z Zhou, MJ Sergeant, M Achtman - PLoS genetics, 2018 - journals.plos.org
For many decades, Salmonella enterica has been subdivided by serological properties into
serovars or further subdivided for epidemiological tracing by a variety of diagnostic tests with …

The source of the Black Death in fourteenth-century central Eurasia

MA Spyrou, L Musralina, GA Gnecchi Ruscone… - Nature, 2022 - nature.com
The origin of the medieval Black Death pandemic (ad 1346–1353) has been a topic of
continuous investigation because of the pandemic's extensive demographic impact and long …

[HTML][HTML] Reconstruction of ancient microbial genomes from the human gut

MC Wibowo, Z Yang, M Borry, A Hübner, KD Huang… - Nature, 2021 - nature.com
Loss of gut microbial diversity,,,,–in industrial populations is associated with chronic
diseases, underscoring the importance of studying our ancestral gut microbiome. However …

The evolution and changing ecology of the African hominid oral microbiome

JA Fellows Yates, IM Velsko, F Aron… - Proceedings of the …, 2021 - National Acad Sciences
The oral microbiome plays key roles in human biology, health, and disease, but little is
known about the global diversity, variation, or evolution of this microbial community. To …

Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and ecology of plague

A Andrades Valtueña, GU Neumann… - Proceedings of the …, 2022 - National Acad Sciences
The bacterial pathogen Yersinia pestis gave rise to devastating outbreaks throughout
human history, and ancient DNA evidence has shown it afflicted human populations as far …

Ten millennia of hepatitis B virus evolution

A Kocher, L Papac, R Barquera, FM Key, MA Spyrou… - Science, 2021 - science.org
Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health
problem, but its past diversity and dispersal routes are largely unknown. We generated HBV …

Ancient pathogen genomics as an emerging tool for infectious disease research

MA Spyrou, KI Bos, A Herbig, J Krause - Nature Reviews Genetics, 2019 - nature.com
Over the past decade, a genomics revolution, made possible through the development of
high-throughput sequencing, has triggered considerable progress in the study of ancient …

[HTML][HTML] Metagenomic and metatranscriptomic analyses reveal activity and hosts of antibiotic resistance genes in activated sludge

Z Liu, U Klümper, Y Liu, Y Yang, Q Wei, JG Lin… - Environment …, 2019 - Elsevier
Wastewater treatment plants (WWTPs) are a source and reservoir for subsequent spread of
various antibiotic resistance genes (ARGs). However, little is known about the activity and …

Early contact between late farming and pastoralist societies in southeastern Europe

S Penske, AB Rohrlach, A Childebayeva… - Nature, 2023 - nature.com
Archaeogenetic studies have described two main genetic turnover events in prehistoric
western Eurasia: one associated with the spread of farming and a sedentary lifestyle starting …