Molecular and cellular mechanisms of propolis and its polyphenolic compounds against cancer

N Oršolić, M Jazvinšćak Jembrek - International journal of molecular …, 2022 - mdpi.com
In recent years, interest in natural products such as alternative sources of pharmaceuticals
for numerous chronic diseases, including tumors, has been renewed. Propolis, a natural …

Allergic inflammation: Effect of propolis and its flavonoids

N Oršolić - Molecules, 2022 - mdpi.com
The incidence of allergic diseases and their complications are increasing worldwide. Today,
people increasingly use natural products, which has been termed a “return to nature” …

Quercetin activates vitamin D receptor and ameliorates breast cancer induced hepatic inflammation and fibrosis

NG Sannappa Gowda, VD Shiragannavar… - Frontiers in …, 2023 - frontiersin.org
Aims To explore the hepatoprotective role of quercetin and its novel molecular mechanism
of action on breast cancer associated hepatic inflammation and fibrosis via Vitamin D …

Microvascularized tumor assembloids model for drug delivery evaluation in colorectal cancer-derived peritoneal metastasis

Q Lv, Y Wang, Z Xiong, Y Xue, J Li, M Chen, K Zhou… - Acta Biomaterialia, 2023 - Elsevier
Peritoneal metastasis (PM) is a fatal state of colorectal cancer, and only a few patients may
benefit from systemic chemotherapy. Although hyperthermic intraperitoneal chemotherapy …

Modulation of TLR/NF-κB/NLRP signaling by bioactive phytocompounds: A promising strategy to augment cancer chemotherapy and immunotherapy

S Fakhri, SZ Moradi, A Yarmohammadi… - Frontiers in …, 2022 - frontiersin.org
Background Tumors often progress to a more aggressive phenotype to resist drugs. Multiple
dysregulated pathways are behind this tumor behavior which is known as cancer …

The role of hyperthermia in potentiation of anti-angiogenic effect of cisplatin and resveratrol in mice bearing solid form of ehrlich ascites tumour

D Kučan, N Oršolić, D Odeh, S Ramić… - International journal of …, 2023 - mdpi.com
The aim of this study was to investigate the therapeutic potential of resveratrol in
combination with cisplatin on the inhibition of tumour angiogenesis, growth, and …

Effects of natural products on cisplatin ototoxicity and chemotherapeutic efficacy

LP Rybak, I Alberts, S Patel… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Cisplatin is a very effective chemotherapeutic agent against a variety of solid
tumors. Unfortunately, cisplatin causes permanent sensorineural hearing loss in at least two …

A scalable hyperthermic intravesical chemotherapy (HIVEC) setup for rat models of bladder cancer

JW Van Hattum, EM Scutigliani, R Helderman… - Scientific reports, 2022 - nature.com
Hyperthermic intravesical chemotherapy (HIVEC)—whereby the bladder is heated to±43° C
during a chemotherapy instillation—can improve outcomes of non-muscle invasive bladder …

Iron metabolism: an emerging therapeutic target underlying the anti-cancer effect of quercetin

M Yin, Y Liu, Y Chen - Free Radical Research, 2021 - Taylor & Francis
Iron, an essential micronutrient for all kinds of cells, is essential for the balance of body
internal environment. Notably, cancer cells exhibit a strong dependence on iron and require …

Properties of flavonoids in the treatment of bladder cancer

Y Lv, Z Liu, H Jia, Y Xiu, Z Liu… - Experimental and …, 2022 - spandidos-publications.com
Given its high recurrence and rapid progress, bladder cancer (BLCA) treatment has become
a major problem for clinicians. BLCA is difficult to control even with surgical resection and …