Transposable elements (TEs) have a unique ability to mobilize to new genomic locations,
and the major advance of second-generation DNA sequencing has provided insights into …

Transposable elements (TEs) or “jumping genes” historically have been disparaged as a
class of “junk DNA” in mammalian genomes (1, 2). The advent of whole genome DNA …

BACKGROUND Spermatozoa are highly differentiated, transcriptionally inert cells
characterized by a compact nucleus with minimal cytoplasm. Nevertheless they contain a …

The completion of the human genome reference sequence ushered in a new era for the
study and discovery of human transposable elements. It now is undeniable that …

After parturition, the uterus undergoes marked remodelling during involution; however, little
is known of the hormonal, cellular and molecular mechanisms that regulate this process …

SINE-VNTR-Alus (SVA) are non-autonomous hominid specific retrotransposons that are
associated with disease in humans. SVAs are evolutionarily young and presumably …

Abstract Long interspersed element-1 (LINE-1 or L1) retrotransposons account for nearly
17% of human genomic DNA and represent a major evolutionary force that has reshaped …

Human endogenous retroviruses (HERVs) constitute 5–8% of human genomic DNA and are
replication incompetent despite expression of individual HERV genes from different …

The major advantage of mRNA vaccines over more conventional approaches is their
potential for rapid development and large-scale deployment in pandemic situations. In the …

In many species the mutation rate is higher in males than in females, a phenomenon
denoted as male mutation bias. This is often observed in animals where males produce …