Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

Recent progress of graphene oxide as a potential vaccine carrier and adjuvant

W Cao, L He, W Cao, X Huang, K Jia, J Dai - Acta biomaterialia, 2020 - Elsevier
Vaccine is one of the most effective strategies for preventing and controlling infectious
diseases and some noninfectious diseases, especially cancers. Adjuvants and carriers have …

Injectable dual-scale mesoporous silica cancer vaccine enabling efficient delivery of antigen/adjuvant-loaded nanoparticles to dendritic cells recruited in local …

TL Nguyen, BG Cha, Y Choi, J Im, J Kim - Biomaterials, 2020 - Elsevier
Despite the potential of nanoparticle-based vaccines, their therapeutic efficacy for cancer
immunotherapy is limited. To elicit robust antigen-specific adaptive immune responses …

Application of nano-delivery systems in lymph nodes for tumor immunotherapy

Y Xia, S Fu, Q Ma, Y Liu, N Zhang - Nano-micro letters, 2023 - Springer
Immunotherapy has become a promising research “hotspot” in cancer treatment.“Soldier”
immune cells are not uniform throughout the body; they accumulate mostly in the immune …

Biomaterial scaffold-based local drug delivery systems for cancer immunotherapy

C Yang, NT Blum, J Lin, J Qu, P Huang - Science Bulletin, 2020 - Elsevier
Immunotherapy has attracted tremendous attention due to the remarkable clinical successes
for treating a broad spectrum of tumors. One challenge for cancer immunotherapy is the …

How are natural-based polymers shaping the future of cancer immunotherapy—a review

DB Rodrigues, RL Reis, RP Pirraco - Polymer Reviews, 2024 - Taylor & Francis
With the increasing knowledge of cancer pathophysiology, new therapeutics based on the
modulation of the immune system have been developed, overcoming many of the …

Long-term vaccine delivery and immunological responses using biodegradable polymer-based carriers

A Malek-Khatabi, Z Tabandeh, A Nouri… - ACS Applied Bio …, 2022 - ACS Publications
Biodegradable polymers are largely employed in the biomedical field, ranging from tissue
regeneration to drug/vaccine delivery. The biodegradable polymers are highly …

Leveraging biomaterials for enhancing T cell immunotherapy

Z Liao, W Zhang, H Zheng, Y Wang, J Yu, H Li… - Journal of Controlled …, 2022 - Elsevier
The dynamic roles of T cells in the immune system to recognize and destroy the infected or
mutated cells render T cell therapy a prospective treatment for a variety of diseases …

Implantable and injectable biomaterial scaffolds for cancer immunotherapy

J Li, Y Luo, B Li, Y Xia, H Wang, C Fu - Frontiers in Bioengineering …, 2020 - frontiersin.org
Cancer immunotherapy has become an emerging strategy recently producing durable
immune responses in patients with varieties of malignant tumors. However, the main …

Flexible polycaprolactone and polycaprolactone/graphene scaffolds for tissue engineering

S Evlashin, P Dyakonov, M Tarkhov, S Dagesyan… - Materials, 2019 - mdpi.com
Developing bone scaffolds can greatly improve the patient's quality of life by accelerating the
rehabilitation process. In this paper, we studied the process of composite polycaprolactone …