Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development

F Lescroart, S Chabab, X Lin, S Rulands… - Nature cell …, 2014 - nature.com
Cardiac development arises from two sources of mesoderm progenitors, the first heart field
(FHF) and the second (SHF). Mesp1 has been proposed to mark the most primitive …

Personalized immunotherapy against several neuronal and brain tumors

S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Teneurins: important regulators of neural circuitry

TR Young, CA Leamey - The international journal of biochemistry & cell …, 2009 - Elsevier
Teneurin (Ten-m/Odz) molecules represent a highly conserved family of four type II
transmembrane proteins in vertebrates (Ten-m1–4), which exist as homodimers and …

Structural basis for teneurin function in circuit-wiring: a toxin motif at the synapse

J Li, M Shalev-Benami, R Sando, X Jiang, A Kibrom… - Cell, 2018 - cell.com
Teneurins (TENs) are cell-surface adhesion proteins with critical roles in tissue development
and axon guidance. Here, we report the 3.1-Å cryoelectron microscopy structure of the …

Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands

X Zhang, PY Lin, K Liakath-Ali, TC Südhof - Nature Communications, 2022 - nature.com
Extensive studies concluded that homophilic interactions between pre-and postsynaptic
teneurins, evolutionarily conserved cell-adhesion molecules, encode the specificity of …

Ancient interaction between the teneurin C-terminal associated peptides (TCAP) and latrophilin ligand-receptor coupling: a role in behavior

R Woelfle, AL D'Aquila, T Pavlović, M Husić… - Frontiers in …, 2015 - frontiersin.org
Teneurins are multifunctional transmembrane proteins that are found in all multicellular
animals and exist as four paralogous forms in vertebrates. They are highly expressed in the …

An LRR receptor-teneurin system directs planar polarity at compartment boundaries

AC Paré, P Naik, J Shi, Z Mirman, KH Palmquist… - Developmental cell, 2019 - cell.com
Epithelial cells dynamically self-organize in response to extracellular spatial cues relayed by
cell-surface receptors. During convergent extension in Drosophila, Toll-related receptors …

Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS

N Suzuki, M Fukushi, K Kosaki, AD Doyle… - Journal of …, 2012 - Soc Neuroscience
Myelination is essential for proper functioning of the CNS. In this study, we have identified a
mouse mutation, designated furue, which causes tremors and hypomyelination in the CNS …

A study of vertebra number in pigs confirms the association of vertnin and reveals additional QTL

GA Rohrer, DJ Nonneman, RT Wiedmann… - BMC genetics, 2015 - Springer
Background Formation of the vertebral column is a critical developmental stage in mammals.
The strict control of this process has resulted in little variation in number of vertebrae across …

Genomewide discovery and classification of candidate ovarian fertility genes in the mouse

TD Gallardo, GB John, L Shirley, CM Contreras… - Genetics, 2007 - academic.oup.com
Female infertility syndromes are among the most prevalent chronic health disorders in
women, but their genetic basis remains unknown because of uncertainty regarding the …