[HTML][HTML] PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up
MC Operti, A Bernhardt, S Grimm, A Engel… - International Journal of …, 2021 - Elsevier
Nanomedicines based on poly (lactic-co-glycolic acid)(PLGA) carriers offer tremendous
opportunities for biomedical research. Although several PLGA-based systems have already …
opportunities for biomedical research. Although several PLGA-based systems have already …
Polymeric nanoparticles: A study on the preparation variables and characterization methods
CIC Crucho, MT Barros - Materials Science and Engineering: C, 2017 - Elsevier
Since the emergence of Nanotechnology in the past decades, the development and design
of nanomaterials has become an important field of research. An emerging component in this …
of nanomaterials has become an important field of research. An emerging component in this …
Exosome detection via the ultrafast-isolation system: EXODUS
Exosomes have shown great potential in disease diagnostics and therapeutics. However,
current isolation approaches are burdensome and suffer from low speed, yield and purity …
current isolation approaches are burdensome and suffer from low speed, yield and purity …
Polymeric micelles for ocular drug delivery: From structural frameworks to recent preclinical studies
Effective intraocular drug delivery poses a major challenge due to the presence of various
elimination mechanisms and physiological barriers that result in low ocular bioavailability …
elimination mechanisms and physiological barriers that result in low ocular bioavailability …
Methods for the preparation and manufacture of polymeric nanoparticles
C Vauthier, K Bouchemal - Pharmaceutical research, 2009 - Springer
This review summarizes the different methods of preparation of polymer nanoparticles
including nanospheres and nanocapsules. The first part summarizes the basic principle of …
including nanospheres and nanocapsules. The first part summarizes the basic principle of …
Toward greener nanosynthesis
JA Dahl, BLS Maddux, JE Hutchison - Chemical reviews, 2007 - ACS Publications
During the past decade, scientists have developed techniques for synthesizing and
characterizing many new materials with at least one dimension on the nanoscale, including …
characterizing many new materials with at least one dimension on the nanoscale, including …
Acoustic separation and concentration of exosomes for nucleotide detection: ASCENDx
Efficient isolation and analysis of exosomal biomarkers hold transformative potential in
biomedical applications. However, current methods are prone to contamination and require …
biomedical applications. However, current methods are prone to contamination and require …
Recent advances in polymeric nanoparticle-encapsulated drugs against intracellular infections
A Sánchez, SP Mejía, J Orozco - Molecules, 2020 - mdpi.com
Polymeric nanocarriers (PNs) have demonstrated to be a promising alternative to treat
intracellular infections. They have outstanding performance in delivering antimicrobials …
intracellular infections. They have outstanding performance in delivering antimicrobials …
Chitosans for delivery of nucleic acids
MD Buschmann, A Merzouki, M Lavertu… - Advanced drug delivery …, 2013 - Elsevier
Alternatives to efficient viral vectors in gene therapy are desired because of their poor safety
profiles. Chitosan is a promising non-viral nucleotide delivery vector because of its …
profiles. Chitosan is a promising non-viral nucleotide delivery vector because of its …
Purification processes of polymeric nanoparticles: How to improve their clinical translation?
SF Tehrani, P Bharadwaj, JL Chain… - Journal of Controlled …, 2023 - Elsevier
Polymeric nanoparticles, as revolutionary nanomedicines, have offered a new class of
diagnostic and therapeutic solutions for a multitude of diseases. With its immense potential …
diagnostic and therapeutic solutions for a multitude of diseases. With its immense potential …