[HTML][HTML] Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre …

CE Coles, CL Griffin, AM Kirby, J Titley, RK Agrawal… - The Lancet, 2017 - thelancet.com
Background Local cancer relapse risk after breast conservation surgery followed by
radiotherapy has fallen sharply in many countries, and is influenced by patient age and …

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer …

JS Vaidya, M Bulsara, M Baum, F Wenz, S Massarut… - bmj, 2020 - bmj.com
Objective To determine whether risk adapted intraoperative radiotherapy, delivered as a
single dose during lumpectomy, can effectively replace postoperative whole breast external …

Partial breast irradiation versus whole breast radiotherapy for early breast cancer

BE Hickey, M Lehman - Cochrane Database of Systematic …, 2021 - cochranelibrary.com
Background Breast‐conserving therapy for women with breast cancer consists of local
excision of the tumour (achieving clear margins) followed by radiotherapy (RT). Most true …

[HTML][HTML] Global adoption of single-shot targeted intraoperative radiotherapy (TARGIT-IORT) for breast cancer—better for patients, better for healthcare systems

JS Vaidya, UJ Vaidya, M Baum, MK Bulsara… - Frontiers in …, 2022 - frontiersin.org
Background: TARGeted Intraoperative radioTherapy (TARGIT-IORT), delivers radiotherapy
targeted to the fresh tumour bed exposed immediately after lumpectomy for breast cancer …

[HTML][HTML] Comparative efficacy of intraoperative radiotherapy and external boost irradiation in early-stage breast cancer: a systematic review and meta-analysis

J Liu, X Shi, Z Niu, C Qian - PeerJ, 2023 - peerj.com
External boost radiotherapy (EBRT) and intraoperative radiotherapy (IORT) are shown to be
effective in patients with early-stage breast cancer. However, the difference between IORT …

[HTML][HTML] Case Report: Intraoperative radiotherapy as the new standard of care for breast cancer patients with disabling health conditions or impairments

M Omosule, S De Silva-Minor, N Coombs - Frontiers in Oncology, 2023 - frontiersin.org
In selected patients, intraoperative radiotherapy (IORT) offers an alternative to standard
external beam radiotherapy (EBRT) while providing equivalent breast cancer control …

Intraoperative partial irradiation for highly selected patients with breast cancer: Results of the INTRAOBS prospective study

C Lemanski, C Bourgier, R Draghici, S Thezenas… - Cancer …, 2020 - Elsevier
Purpose To evaluate our long-term experience on one-day breast intraoperative
radiotherapy (IORT) given as sole radiation treatment to selected patients with breast …

[HTML][HTML] Prospective comparison of hypofractionated versus normofractionated intensity-modulated radiotherapy in breast cancer: late toxicity results of the non …

GR Sarria, G Welzel, M Polednik, F Wenz… - Frontiers in …, 2022 - frontiersin.org
Purpose To compare the late toxicity profile of hypofractionation and normofractionation for
whole-breast radiotherapy in breast cancer (BC) patients after conserving surgery. Methods …

Health services research in brachytherapy: current understanding and future challenges

N Defourny, P Mackenzie, K Spencer - Clinical Oncology, 2023 - Elsevier
Brachytherapy is an integral component of cancer care. Widespread concerns have been
expressed though about the need for greater brachytherapy availability across many …

Targeted radiotherapy for early breast cancer

JS Vaidya, M Bulsara, F Wenz, JS Tobias, D Joseph… - The Lancet, 2018 - thelancet.com
Thankfully, policy making is for a democratic government, not agencies. However, PHE is
not “passive” in policy making. 1 We influence policy to protect and improve health and to …