Super-resolution optoacoustic imaging of microvascular structures deep in mammalian
tissues has so far been impeded by strong absorption from densely-packed red blood cells …

Microglia play key roles in the post‐ischemic inflammatory response and damaged tissue
removal reacting rapidly to the disturbances caused by ischemia and working to restore the …

Spreading depolarizations (SDs) are characterized by near-complete breakdown of the
transmembrane ion gradients, cytotoxic edema, and glutamate release. SDs are associated …

Anesthesia is a major confounding factor in preclinical stroke research as stroke rarely
occurs in sedated patients. Moreover, anesthesia affects both brain functions and the stroke …

Temperature control in severe acute brain injury (SABI) is a key component of acute
management. This manuscript delves into the complex role of temperature management in …

Ischemic stroke occurs abruptly causing sudden neurologic deficits, and therefore, very little
is known about hemodynamic perturbations in the brain immediately after stroke onset …

Spontaneous cerebral vasomotion, characterized by∼ 0.1 Hz rhythmic contractility, is crucial
for brain homeostasis. However, our understanding of vasomotion is limited due to a lack of …

Anesthesia is a major confounding factor in preclinical stroke research as stroke rarely
occurs in sedated patients. Moreover, anesthesia affects both brain functions and the stroke …

Purpose: Our aim was to use intracortical recording to enable the tracking of ischemic infarct
development over the first few critical hours of ischemia with a high time resolution in pigs …

Background Despite recanalization after ischemic stroke, neurovascular coupling, ie, the
local hyperaemic response to neuronal activity, is impaired in peri-ischemic brain regions …