Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review

S Cortese, M Solmi, G Michelini, A Bellato… - World …, 2023 - Wiley Online Library
Neurodevelopmental disorders–including attention‐deficit/hyperactivity disorder (ADHD),
autism spectrum disorder, communication disorders, intellectual disability, motor disorders …

An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder

BS Da Silva, EH Grevet, LCF Silva, JKN Ramos… - Discover Mental …, 2023 - Springer
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition
characterized by developmentally inappropriate symptoms of inattention and/or …

New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications

OA Andreassen, GFL Hindley, O Frei… - World …, 2023 - Wiley Online Library
Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

[HTML][HTML] Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors

N Mullins, JE Kang, AI Campos, JRI Coleman… - Biological …, 2022 - Elsevier
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts,
which occur far more frequently, are a major source of disability and social and economic …

CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice

S Sanchez-Roige, MV Jennings, HHA Thorpe… - Translational …, 2023 - nature.com
Impulsivity is a multidimensional heritable phenotype that broadly refers to the tendency to
act prematurely and is associated with multiple forms of psychopathology, including …

Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder

VM Rajagopal, J Duan, L Vilar-Ribó, J Grove… - Nature …, 2022 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder with onset
in childhood (childhood ADHD); two-thirds of affected individuals continue to have ADHD in …

Genetic patterning for child psychopathology is distinct from that for adults and implicates fetal cerebellar development

DE Hughes, K Kunitoki, S Elyounssi, M Luo… - Nature …, 2023 - nature.com
Childhood psychiatric symptoms are often diffuse but can coalesce into discrete mental
illnesses during late adolescence. We leveraged polygenic scores (PGSs) to parse genomic …

[HTML][HTML] ADHD symptoms in neurometabolic diseases: Underlying mechanisms and clinical implications

SC Homaei, H Barone, R Kleppe, N Betari… - … & biobehavioral reviews, 2022 - Elsevier
Neurometabolic diseases (NMDs) are typically caused by genetic abnormalities affecting
enzyme functions, which in turn interfere with normal development and activity of the …

Non-mental diseases associated with ADHD across the lifespan: Fidgety Philipp and Pippi Longstocking at risk of multimorbidity?

S Kittel-Schneider, G Arteaga-Henriquez… - Neuroscience & …, 2022 - Elsevier
Several non-mental diseases seem to be associated with an increased risk of ADHD and
ADHD seems to be associated with increased risk for non-mental diseases. The underlying …

Gut microbiota signature in treatment-naïve attention-deficit/hyperactivity disorder

V Richarte, C Sánchez-Mora, M Corrales… - Translational …, 2021 - nature.com
Compelling evidence supports alterations in gut microbial diversity, bacterial composition,
and/or relative abundance of several bacterial taxa in attention-deficit/hyperactivity disorder …