Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Neurons that synthesize and release 5-hydroxytryptamine (5-HT; serotonin) express a core
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …

Epilepsy is a complex neurological syndrome characterized by seizures resulting from
neuronal hyperexcitability and sudden and synchronized bursts of electrical discharges …

Astrocytes are housekeepers of the central nervous system (CNS) and are important for
CNS development, homeostasis and defence. They communicate with neurones and other …

Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …

▪ Abstract Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the
presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release …

J. Neurochem.(2012) 121, 4–27. Abstract Neuroglial cells define brain homeostasis and
mount defense against pathological insults. Astroglia regulate neurogenesis and …

Mesocotical dopamine (DA) inputs to the prefrontal cortex (PFC) play a crtical role in normal
cognitive process and neuropsychiatic pathologies. This DA input regulates aspects of …

The past decade has seen an explosion of research on roles of neuron-astrocyte
interactions in the control of brain function. We highlight recent studies performed on the …

In the past 20 years, an extra layer of information processing, in addition to that provided by
neurons, has been proposed for the CNS. Neuronally evoked increases of the intracellular …