Any aspect of cell activity is regulated by extracellular signals that are recognized, decoded,
and transduced inside the cell via different classes of plasma membrane receptors. 1À3 G …

The design and development of selective ligands for the human OT (oxytocin) and AVP
(arginine vasopressin) receptors is a big challenge since the different receptor subtypes and …

Vasopressin and oxytocin are intrinsically disordered cyclic nonapeptides belonging to a
family of neurohypophysial hormones. Although unique in their functions, these peptides …

Statins competitively inhibit hepatic 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase,
resulting in reduced plasma total and low‐density lipoprotein cholesterol levels. Recently, it …

The study of energy landscapes has led to a good understanding of how and why proteins
and nucleic acids adopt their native structure. Through evolution, sequences have adapted …

Aims Non-peptide ligands of oxytocin receptor (OTR) have promising potentialities as
therapeutic agents with improved pharmacological properties. WAY-267,464 is a non …

In this study, four cyclic vasopressin (CYFQNCPRG-NH2, AVP) analogues substituted at
positions 2 and 3 with four combinations of enantiomers of N-methylphenylalanine have …

Abstract Vasopressin (CYFQNCPRG‐NH2, AVP) is a semicyclic endogenous peptide, which
exerts a variety of biological effects in mammals. The main physiological roles of AVP are …

We present a joint experimental and theoretical investigation of the structural and optical
properties of copper− oxytocin dications in the gas phase. Ion mobility and UV …

Background Oxytocin (OT), synthesized in the heart, has the ability to heal injured hearts
and to promote cardiomyogenesis from stem cells. Recently, we reported that the OT-GKR …