There are many studies on certain skin cell specifications and their contribution to wound
healing. In this review, we provide an overview of dermal cell heterogeneity and their …

Hair follicle (HF) formation in developing embryonic skin requires stepwise signalling
between the epithelial epidermis and mesenchymal dermis, and their specialized …

Understanding global communications among cells requires accurate representation of cell-
cell signaling links and effective systems-level analyses of those links. We construct a …

Human prenatal skin is populated by innate immune cells, including macrophages, but
whether they act solely in immunity or have additional functions in morphogenesis is …

Tissue stem cells are generated from a population of embryonic progenitors through organ-
specific morphogenetic events,. Although tissue stem cells are central to organ homeostasis …

A wealth of specialized cell populations within the skin facilitates its hair-producing,
protective, sensory, and thermoregulatory functions. How the vast cell-type diversity and …

Hair follicle stem cells are regulated by dermal papilla fibroblasts, their principal signaling
niche. Overactivation of Hedgehog signaling in the niche dramatically accelerates hair …

During vertebrate organogenesis, increases in morphological complexity are tightly coupled
to morphogen expression. In this work, we studied how morphogens influence self …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Delineating molecular and cellular events that precede appendage morphogenesis has
been challenging due to the inability to distinguish quantitative molecular differences …