Despite the increasing use and success of interventional coronary reperfusion strategies,
morbidity and mortality from acute myocardial infarction are still substantial. Myocardial …

The incidence of ST segment elevation myocardial infarction (STEMI) has decreased over
the last two decades in developed countries, but mortality from STEMI despite widespread …

Reperfusion is mandatory to salvage ischemic myocardium from infarction, but reperfusion
per se contributes to injury and ultimate infarct size. Therefore, cardioprotection beyond that …

In remote ischemic conditioning (RIC), brief, reversible episodes of ischemia with
reperfusion in one vascular bed, tissue, or organ confer a global protective phenotype and …

Ischaemic heart disease and the heart failure that often results, remain the leading causes of
death and disability in Europe and worldwide. As such, in order to prevent heart failure and …

The translation from numerous successful animal experiments on cardioprotection beyond
that by reperfusion to clinical practice has to date been disappointing. Animal experiments …

Ischaemic heart disease (IHD) remains the leading cause of death and disability in Europe
and worldwide. A major cause of morbidity and mortality in IHD patients is an acute ST …

Despite prompt reperfusion by primary percutaneous coronary intervention (PPCI), the
mortality and morbidity of patients presenting with an acute ST-segment elevation …

Protein kinase C (PKC) and Protein kinase D (PKD) isoforms can sense diacylglycerol
(DAG) generated in the different cellular compartments in various physiological processes …

Radiation-induced endothelial/vascular injury is a major complicating factor in radiotherapy
and a leading cause of morbidity and mortality in nuclear or radiological catastrophes …