Involvement of astrocytes in Alzheimer's disease from a neuroinflammatory and oxidative stress perspective

RE González-Reyes, MO Nava-Mesa… - Frontiers in molecular …, 2017 - frontiersin.org
Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …

Adverse effects of anabolic-androgenic steroids: a literature review

GD Albano, F Amico, G Cocimano, A Liberto… - Healthcare, 2021 - mdpi.com
Anabolic-androgenic steroids (AASs) are a large group of molecules including
endogenously produced androgens, such as testosterone, as well as synthetically …

Role of nuclear factor kappa B (NF-κB) signalling in neurodegenerative diseases: an mechanistic approach

S Singh, TG Singh - Current Neuropharmacology, 2020 - ingentaconnect.com
A transcriptional regulatory nuclear factor kappa B (NF-ΚB) protein is a modulator of cellular
biological activity via binding to a promoter region in the nucleus and transcribing various …

Neuroinflammation in schizophrenia: the key role of the WNT/β-catenin pathway

A Vallée - International Journal of Molecular Sciences, 2022 - mdpi.com
Schizophrenia is a very complex syndrome involving widespread brain multi-
dysconnectivity. Schizophrenia is marked by cognitive, behavioral, and emotional …

Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets

V Mishra, J Banga, P Silveyra - Pharmacology & Therapeutics, 2018 - Elsevier
Asthma is a complex inflammatory disease characterized by airway inflammation and
hyperresponsiveness. The mechanisms associated with the development and progression …

The heart as a target for deltamethrin toxicity: Inhibition of Nrf2/HO-1 pathway induces oxidative stress and results in inflammation and apoptosis

X Yang, Y Fang, J Hou, X Wang, J Li, S Li, X Zheng… - Chemosphere, 2022 - Elsevier
As a synthetic pyrethroid pesticide, deltamethrin (DLM) is widely employed in veterinary
medicine and farming, and DLM-triggered oxidative stress largely causes serious harm to …

Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach

S Kucukler, F Benzer, S Yildirim, C Gur… - … Trace Element Research, 2021 - Springer
In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …

Nandrolone decanoate: use, abuse and side effects

FG Patanè, A Liberto, AN Maria Maglitto, P Malandrino… - Medicina, 2020 - mdpi.com
Background and Objectives: Androgens play a significant role in the development of male
reproductive organs. The clinical use of synthetic testosterone derivatives, such as …

Reactive oxygen species signaling and oxidative stress: transcriptional regulation and evolution

Y Hong, A Boiti, D Vallone, NS Foulkes - Antioxidants, 2024 - mdpi.com
Since the evolution of the aerobic metabolism, reactive oxygen species (ROS) have
represented significant challenges to diverse life forms. In recent decades, increasing …

Sulforaphane prevents chromium-induced lung injury in rats via activation of the Akt/GSK-3β/Fyn pathway

Y Lv, H Jiang, S Li, B Han, Y Liu, D Yang, J Li… - Environmental …, 2020 - Elsevier
Chromium (Cr) is an internationally recognized carcinogenic hazard that causes serious
pulmonary toxicity. However, Cr-induced pulmonary toxicity lacks effective treatment to date …