Empirical profile mixture models for phylogenetic reconstruction

L Si Quang, O Gascuel, N Lartillot - Bioinformatics, 2008 - academic.oup.com
Motivation: Previous studies have shown that accounting for site-specific amino acid
replacement patterns using mixtures of stationary probability profiles offers a promising …

Modeling protein evolution with several amino acid replacement matrices depending on site rates

SQ Le, CC Dang, O Gascuel - Molecular biology and evolution, 2012 - academic.oup.com
Most protein substitution models use a single amino acid replacement matrix summarizing
the biochemical properties of amino acids. However, site evolution is highly heterogeneous …

Phylogenetic mixture models for proteins

SQ Le, N Lartillot, O Gascuel - … Transactions of the …, 2008 - royalsocietypublishing.org
Standard protein substitution models use a single amino acid replacement rate matrix that
summarizes the biological, chemical and physical properties of amino acids. However, site …

Accounting for solvent accessibility and secondary structure in protein phylogenetics is clearly beneficial

SQ Le, O Gascuel - Systematic Biology, 2010 - academic.oup.com
Amino acid substitution models are essential to most methods to infer phylogenies from
protein data. These models represent the ways in which proteins evolve and substitutions …

Evolution of plant MADS box transcription factors: evidence for shifts in selection associated with early angiosperm diversification and concerted gene duplications

H Shan, L Zahn, S Guindon, PK Wall… - Molecular biology …, 2009 - academic.oup.com
Phylogenomic analyses show that gene and genome duplication events have led to the
diversification of transcription factor gene families throughout the evolutionary history of land …

[PDF][PDF] Divergence dating using mixed effects clock modelling: An application to HIV-1

M Bletsa, MA Suchard, X Ji, S Gryseels… - Virus …, 2019 - academic.oup.com
The need to estimate divergence times in evolutionary histories in the presence of various
sources of substitution rate variation has stimulated a rich development of relaxed molecular …

[图书][B] Genetics and evolution of infectious diseases

M Tibayrenc - 2024 - books.google.com
Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of
infectious diseases and their continued impact on the health of populations, especially in …

Identifiability of a Markovian model of molecular evolution with gamma-distributed rates

ES Allman, C Ané, JA Rhodes - Advances in Applied Probability, 2008 - cambridge.org
Inference of evolutionary trees and rates from biological sequences is commonly performed
using continuous-time Markov models of character change. The Markov process evolves …

[图书][B] Gene und Stammbäume: ein Handbuch zur molekularen Phylogenetik

V Knoop, K Müller - 2009 - books.google.com
Gene, Genome und Sequenzen auf der einen Seite, Algorithmen, Computer und Informatik
auf der anderen-sie üben Faszination aus, halten aber viele Interessierte auf respektvolle …

Performance of standard and stochastic branch-site models for detecting positive selection among coding sequences

A Lu, S Guindon - Molecular biology and evolution, 2014 - academic.oup.com
The branch-site model is a widely popular approach that accommodates for the lineage-and
the site-specific heterogeneity of natural selection regimes among coding sequences. This …