Natural killer (NK) cells are lymphocytes of the innate immune response characterized by
their role in the destruction of tumor cells. Activation of NK cells depend on a fine balance …

The functional capacities of natural killer (NK) cells differ within and between individuals,
reflecting considerable genetic variation.'Licensing/arming','disarming', and 'tuning'are …

Background Recurrence and metastasis are the leading causes of tumour-related death in
patients with oesophageal squamous cell carcinoma (ESCC). Tumour-infiltrating natural …

The development of innate lymphoid cell (ILC) transcription factor reporter mice has shown a
previously unexpected complexity in ILC hematopoiesis. Using novel polychromic mice to …

Natural killer (NK) cells represent a critical defense against viral infections and cancers. NK
cells require integration of activating and inhibitory NK cell receptors to detect target cells …

Interactions between human leukocyte antigen (HLA) molecules on target cells and the
inhibitory killer cell immunoglobulin-like receptors (KIRs) and heterodimeric inhibitory …

Mesenchymal stromal/stem cells (MSCs) are used in many studies due to their therapeutic
potential, including their differentiative ability and immunomodulatory properties. These cells …

Aneuploidy, the unbalanced state of the chromosome content, represents a hallmark of most
solid tumors, including colorectal cancer. Such aneuploidies result in tumor specific genomic …

The differentiation of human induced pluripotent stem cells (hiPSCs) into T and natural killer
(NK) lymphocytes opens novel possibilities for developmental studies of immune cells and …

Simple Summary This review aims at analyzing an emergent topic regarding the possible
combined use of poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi), anticancer drugs …