Structural basis for the functional properties of the P2X7 receptor for extracellular ATP
The P2X7 receptor, originally known as the P2Z receptor due to its distinctive functional
properties, has a structure characteristic of the ATP-gated ion channel P2X receptor family …
properties, has a structure characteristic of the ATP-gated ion channel P2X receptor family …
P2X receptor activation
T Kawate - Protein Reviews: Volume 19, 2017 - Springer
Abstract Extracellular ATP-gated P2X receptors are trimeric non-selective cation channels
important for many physiological events including immune response and neural …
important for many physiological events including immune response and neural …
Algorithms for structure comparison and analysis: Homology modelling of proteins
M Wiltgen - … of bioinformatics and computational biology: ABC of …, 2018 - books.google.com
Protein structure is uniquely determined by its amino acid sequence. Knowledge of protein
3D structure is of crucial importance for understanding protein function, dynamics and …
3D structure is of crucial importance for understanding protein function, dynamics and …
Protein disulfide isomerase-mediated S-nitrosylation facilitates surface expression of P2X7 receptor following status epilepticus
DS Lee, JE Kim - Journal of neuroinflammation, 2021 - Springer
Abstract Background P2X7 receptor (P2X7R) is an ATP-gated nonselective cationic channel
playing important roles in a variety of physiological functions, including inflammation, and …
playing important roles in a variety of physiological functions, including inflammation, and …
Identification of residues in the first transmembrane domain of the P2X7 that regulates receptor trafficking, sensitization, and dye uptake function
M Rupert, A Bhattacharya, S Sivcev… - Journal of …, 2023 - Wiley Online Library
Abstract P2X receptors (P2X1‐7) are trimeric ion channels activated by extracellular ATP.
Each P2X subunit contains two transmembrane helices (TM1 and TM2). We substituted all …
Each P2X subunit contains two transmembrane helices (TM1 and TM2). We substituted all …
Heterologous expression and patch-clamp recording of P2X receptors in HEK293 cells
LH Jiang, S Roger - Purinergic Signaling: Methods and Protocols, 2020 - Springer
Abstract P2X receptors (P2XRs) are ligand-gated ion channels gated by extracellular
adenosine 5′-triphosphate (ATP) and play a critical role in mediating ATP-induced …
adenosine 5′-triphosphate (ATP) and play a critical role in mediating ATP-induced …
Investigating Natural Product Glycosides as Allosteric Modulators of P2X Purinergic Receptors
E Allum - 2023 - ueaeprints.uea.ac.uk
Natural products have been used traditionally for thousands of years to treat a wide variety
of ailments. The active compounds in Panax ginseng, the ginsenosides, have been shown …
of ailments. The active compounds in Panax ginseng, the ginsenosides, have been shown …
Analysis of the molecular mechanisms of prestin-mediated cochlear amplification via a cysteine accessibility study
J Hartmann - 2021 - archiv.ub.uni-marburg.de
Prestin is the protein being responsible for electromotility in mammals. It is a member of the
SLC26 (Solute Carrier) family, which function as anion transporters. In contrast to the other …
SLC26 (Solute Carrier) family, which function as anion transporters. In contrast to the other …
[PDF][PDF] Analysis of the molecular mechanisms of prestin-mediated cochlear amplification via a cysteine accessibility study
D Oliver - core.ac.uk
Hearing is an invention of evolution. The sense of sound has evolved gradually and is
therefore not found in every animal species. Furthermore, the ear is the vertebrate hearing …
therefore not found in every animal species. Furthermore, the ear is the vertebrate hearing …