The physiology, pathology, and pharmacology of voltage-gated calcium channels and their future therapeutic potential

GW Zamponi, J Striessnig, A Koschak… - Pharmacological …, 2015 - Elsevier
Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

Voltage-gated calcium channels: Determinants of channel function and modulation by inorganic cations

F Neumaier, M Dibue-Adjei, J Hescheler… - Progress in …, 2015 - Elsevier
Voltage-gated calcium channels (VGCCs) represent a key link between electrical signals
and non-electrical processes, such as contraction, secretion and transcription. Evolved to …

Superspreading‐Confined Assembly of Oriented 2D MOF Membranes for Biomimetic Cation‐Regulated Ion Transport

M Qiu, Z Zhu, D Wang, Z Xu, F Xia… - Advanced Functional …, 2024 - Wiley Online Library
Inspired by biological channels, metal‐organic framework (MOF) membranes with sub‐
nanometer sized channels offer an ideal platform to construct high‐performance artificial …

Reproductive impacts and physiological adaptations of zebrafish to elevated dietary nickel

D Alsop, SP Lall, CM Wood - … and Physiology Part C: Toxicology & …, 2014 - Elsevier
Nickel (Ni) concentrations in the environment can rise due to human industrial activities. The
toxicity of waterborne Ni to aquatic animals has been examined in a number of previous …

Neurotransmitters and behavioral alterations induced by nickel exposure

MI Martínez-Martínez… - … , Metabolic & Immune …, 2020 - ingentaconnect.com
Background: Nickel ions (Ni2+) are a heavy metal with wide industrial uses. Environmental
and occupational exposures to Ni are potential risk factors for brain dysfunction and …

Chronic intrathecal infusion of mibefradil, ethosuximide and nickel attenuates nerve ligation-induced pain in rats

YL Chen, ML Tsaur, SW Wang, TY Wang… - British journal of …, 2015 - academic.oup.com
Background T-type Ca2+ channels (TCC) are important for pain transmission, especially the
CaV3. 2 subtype. In this study, we examined the effects of intrathecal TCC blockers in the …

Models of calcium permeation through T-type channels

YM Shuba - Pflügers Archiv-European Journal of Physiology, 2014 - Springer
Ca 2+ entry is indispensable part of intracellular Ca 2+ signaling, which is vital for most of
cellular functions. Low voltage-activated (LVA or T-type) calcium channels belong to the …

Hysteresis of transient populations in absorbing-state systems

OL Kapitanchuk, OM Marchenko, VI Teslenko - Chemical Physics, 2016 - Elsevier
A nonequilibrium density matrix theory is used in order to explicitly describe the hysteresis
interrelation between populations of nonstationary states in an absorbing multi-stage chain …

Nickel affects gill and muscle development in oriental fire-bellied toad (Bombina orientalis) embryos

CJ Park, SH Song, DH Kim, MC Gye - Aquatic Toxicology, 2017 - Elsevier
The developmental toxicity of nickel was examined in the embryos of Bombina orientalis, a
common amphibian in Korea. Based on a standard frog embryo teratogenesis assay, the LC …

Conopeptides as tools for studying pacemaker channels and for the development of novel cardiovascular drugs

AS Depuydt, J Tytgat, S Peigneur - 2022 - lirias.kuleuven.be
Cardiovascular diseases are the leading cause of death in the world, accounting for the
death of 17.9 million people every year. Based on data from the World Health Organization …