[HTML][HTML] Diet, microbiota and gut-lung connection
The gut microbial community (Gut microbiota) is known to impact metabolic functions as well
as immune responses in our body. Diet plays an important role in determining the …
as immune responses in our body. Diet plays an important role in determining the …
CXCR3 in T cell function
JR Groom, AD Luster - Experimental cell research, 2011 - Elsevier
CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …
[PDF][PDF] Regulatory T cell specificity directs tolerance versus allergy against aeroantigens in humans
P Bacher, F Heinrich, U Stervbo, M Nienen… - Cell, 2016 - cell.com
FOXP3+ regulatory T cells (Tregs) maintain tolerance against self-antigens and innocuous
environmental antigens. However, it is still unknown whether Treg-mediated tolerance is …
environmental antigens. However, it is still unknown whether Treg-mediated tolerance is …
CXCR3 ligands: redundant, collaborative and antagonistic functions
JR Groom, AD Luster - Immunology and cell biology, 2011 - Wiley Online Library
CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …
The cytokine network in asthma and chronic obstructive pulmonary disease
PJ Barnes - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
Asthma and chronic obstructive pulmonary disease (COPD) are very common inflammatory
diseases of the airways. They both cause airway narrowing and are increasing in incidence …
diseases of the airways. They both cause airway narrowing and are increasing in incidence …
Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung
LD Faustino, JW Griffith, RA Rahimi, K Nepal… - Nature …, 2020 - nature.com
Abstract Foxp3+ regulatory T (Treg) cells expressing the interleukin (IL)-33 receptor ST2
mediate tissue repair in response to IL-33. Whether Treg cells also respond to the alarmin IL …
mediate tissue repair in response to IL-33. Whether Treg cells also respond to the alarmin IL …
Chemokines and their receptors: drug targets in immunity and inflammation
A Viola, AD Luster - Annu. Rev. Pharmacol. Toxicol., 2008 - annualreviews.org
The chemokine system coordinates leukocyte migration in immunity and inflammation and is
implicated in the pathogenesis of many human diseases. Although several successful …
implicated in the pathogenesis of many human diseases. Although several successful …
Functionally diverse human T cells recognize non-microbial antigens presented by MR1
MHC class I-related molecule MR1 presents riboflavin-and folate-related metabolites to
mucosal-associated invariant T cells, but it is unknown whether MR1 can present alternative …
mucosal-associated invariant T cells, but it is unknown whether MR1 can present alternative …
[HTML][HTML] Trigger-happy resident memory CD4+ T cells inhabit the human lungs
AE Oja, B Piet, C Helbig, R Stark, D Van Der Zwan… - Mucosal …, 2018 - Elsevier
Resident memory T cells (T RM) reside in the lung epithelium and mediate protective
immunity against respiratory pathogens. Although lung CD8+ T RM have been extensively …
immunity against respiratory pathogens. Although lung CD8+ T RM have been extensively …
T cell homing to epithelial barriers in allergic disease
SA Islam, AD Luster - Nature medicine, 2012 - nature.com
Allergic inflammation develops in tissues that have large epithelial surface areas that are
exposed to the environment, such as the lung, skin and gut. In the steady state, antigen …
exposed to the environment, such as the lung, skin and gut. In the steady state, antigen …