Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …

A possible precision-medicine approach to treating obstructive sleep apnoea (OSA) involves
targeting ventilatory instability (elevated loop gain) using supplemental inspired oxygen in …

Rationale: There are at least four key pathophysiological endotypes that contribute to
obstructive sleep apnea (OSA) pathophysiology. These include 1) upper-airway …

Impaired upper airway anatomy is the main cause of obstructive sleep apnea (OSA).
However, there are other important non-anatomical contributors or “endotypes” including …

Current approaches to quantify and diagnose sleep disorders and circadian rhythm
disruption are imprecise, laborious, and often do not relate well to key clinical and health …

The following argument was prepared in response to the question without the knowledge of
the contents of the opposing argument. Obstructive sleep apnea (OSA) is a highly prevalent …

Background A systematic review was carried out on the effect of surgical maxillomandibular
advancement (MMA) on pharyngeal airway (PA) dimensions and the apnoea–hypopnoea …

Background Potassium (K+) channel inhibition has been identified in animal models as a
potential target to increase pharyngeal dilator muscle activity and to treat OSA. However …

Obstructive sleep apnea (OSA) is a common condition with major neurocognitive and
cardiovascular sequelae. 1 The disease is characterized by repetitive collapse of the …