The development of induced pluripotent stem cells has brought unlimited possibilities to the
field of regenerative medicine. This could be ideal for treating osteoarthritis and other …

Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a
peak incidence in adolescents and young adults, conventional and dedifferentiated …

Large articular cartilage defects remain an immense challenge in the field of regenerative
medicine because of their poor intrinsic repair capacity. Currently, the available medical …

Objective Chondroprogenitors have recently gained prominence due to promising results
seen in in vitro and animal studies as a potential contender in cell-based therapy for …

Cartilage derived stem/progenitor cells (CSPCs) have been isolated from a variety of
cartilage sources and are suggested to have high chondrogenic potential. However, their …

Cartilage-derived pluripotent cells reside in hyaline cartilage and fibrocartilage. These cells
have the potential for multidirectional differentiation; can undergo adipogenesis …

Osteoarthritis (OA) is characterised by cartilage destruction; however, there are no specific
drugs available for its treatment. Cartilage-derived stem/progenitor cells (CSPCs) are …

Radiation-induced complications in bone and cartilage are of increasing concern due to
potential long-term effects in cancer survivors. Healthy articular cartilage may be exposed to …

Purpose Chondrocytes, isolated from articular cartilage, are routinely utilized in cell-based
therapeutics for the treatment of cartilage pathologies. However, restoration of the biological …

Recent research has confirmed the presence of Mesenchymal stem cell (MSC)-like
progenitors (MPC) in both normal and osteoarthritic cartilage. However, there is only limited …