Autism spectrum disorder (ASD) is comprised of several conditions characterized by
alterations in social interaction, communication, and repetitive behaviors. Genetic and …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with increasing
prevalence. Over 1,000 risk genes have now been implicated in ASD, suggesting diverse …

Memories become less precise and generalized over time as memory traces reorganize in
hippocampal–cortical networks. Increased time-dependent loss of memory precision is …

Excitatory and inhibitory neurons are connected into microcircuits that generate circuit
output. Central in the hippocampal CA3 microcircuit is the mossy fiber (MF) synapse, which …

The number of genes associated with autism is increasing, but few studies have been
performed on epidemiological cohorts and in isolated populations. Here, we investigated …

Synapses are specialized neuronal cell-cell contacts that underlie network communication
in the mammalian brain. Across neuronal populations and circuits, a diverse set of synapses …

Neurodevelopmental and neuropsychiatric disorders, such as autism spectrum disorders
(ASD), anorexia nervosa (AN), Alzheimer's disease (AD), and schizophrenia (SZ), are …

Schizophrenia, a complex neuropsychiatric disorder, frequently experiences a high rate of
misdiagnosis due to subjective symptom assessment. Consequently, there is an urgent …

Hippocampal CA3 neurons form synapses with CA1 neurons in two layers, stratum oriens
(SO) and stratum radiatum (SR). Each layer develops unique synaptic properties but …

DNA sequence composition determines the topology and stability of G-quadruplexes (G4s).
Bulged G-quadruplex structures (G4-Bs) are a subset of G4s characterized by 3D …