Bioorthogonal chemistry

SL Scinto, DA Bilodeau, R Hincapie, W Lee… - Nature Reviews …, 2021 - nature.com
Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …

Molecular insights into extracellular polymeric substances in activated sludge

HQ Yu - Environmental Science & Technology, 2020 - ACS Publications
Extracellular polymeric substances (EPS) are known to crucially affect the properties and
performance of activated sludge, but the detailed influential mechanisms and the pertinence …

Extracellular polymeric substances of biofilms: suffering from an identity crisis

T Seviour, N Derlon, MS Dueholm, HC Flemming… - Water research, 2019 - Elsevier
Microbial biofilms can be both cause and cure to a range of emerging societal problems
including antimicrobial tolerance, water sanitation, water scarcity and pollution. The …

Chemical reporters for bacterial glycans: development and applications

N Banahene, HW Kavunja, BM Swarts - Chemical reviews, 2021 - ACS Publications
Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …

Cell wall synthesis and remodelling dynamics determine division site architecture and cell shape in Escherichia coli

PP Navarro, A Vettiger, VY Ananda, PM Llopis… - Nature …, 2022 - nature.com
The bacterial division apparatus catalyses the synthesis and remodelling of septal
peptidoglycan (sPG) to build the cell wall layer that fortifies the daughter cell poles …

The bacterial cell wall: from lipid II flipping to polymerization

S Kumar, A Mollo, D Kahne, N Ruiz - Chemical reviews, 2022 - ACS Publications
The peptidoglycan (PG) cell wall is an extra-cytoplasmic glycopeptide polymeric structure
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …

A biocompatible heterogeneous MOF–Cu catalyst for in vivo drug synthesis in targeted subcellular organelles

F Wang, Y Zhang, Z Liu, Z Du, L Zhang… - Angewandte Chemie …, 2019 - Wiley Online Library
As a typical bioorthogonal reaction, the copper‐catalyzed azide–alkyne cycloaddition
(CuAAC) has been used for drug design and synthesis. However, for localized drug …

AIEgens for microorganism‐related visualization and therapy

Z Ye, W He, Z Zhang, Z Qiu, Z Zhao… - Interdisciplinary …, 2023 - Wiley Online Library
Humans and bacteria have always been closely related. However, pathogenic bacteria and
drug‐resistant bacteria pose a certain threat to human life and health. On the other hand …

To view your biomolecule, click inside the cell

V Rigolot, C Biot, C Lion - Angewandte Chemie, 2021 - Wiley Online Library
The surging development of bioorthogonal chemistry has profoundly transformed chemical
biology over the last two decades. Involving chemical partners that specifically react together …

Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis

E Kuru, A Radkov, X Meng, A Egan… - ACS Chemical …, 2019 - ACS Publications
Bacteria exhibit a myriad of different morphologies, through the synthesis and modification of
their essential peptidoglycan (PG) cell wall. Our discovery of af luorescent da mino a cid …